Biomaterial Database

[Radiation ulcers after Cf-252 treatment of patients with cancer of the tongue]. 1984

G F Galantseva, and L I Guseva, and V I Plichko

A study was made of the frequency, clinical appearance and therapeutic methods of radiation injuries in 12 out of 57 patients who were treated for cancer of the tongue using interstitial therapy with 252Cf. The most frequent radiation injuries were observed in patients (6 out of 18, i.e. 34%) who were treated for recurrent and residual tumors after previous radiotherapeutic courses as compared to the treatment of primary malignant lesions in 6 out 39 (15%) patients. The clinical picture of radiation injuries of the tongue presented an ulcer of various sizes. A clinical classification of radiation injuries of the tongue was developed depending on the degree of the manifestations. Among causative factors the most important role is played by an absorbed tumor dose which when exceeding 9 Gy in patients with primary tumors and 8 Gy in patients with recurrent and residual tumors, resulted in radiation injuries. The development of radiation injuries is also influenced by poor hygiene and the oral cavity, and such harmful habits as smoking and alcohol consumption. Conservative therapeutic measures made it possible to achieve a complete epithelization of ulcers.

UI	MeSH Term	Description	Entries
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D011832	Radiation Injuries	Harmful effects of non-experimental exposure to ionizing or non-ionizing radiation in VERTEBRATES.	Radiation Sickness,Radiation Syndrome,Injuries, Radiation,Injury, Radiation,Radiation Injury,Radiation Sicknesses,Radiation Syndromes,Sickness, Radiation,Sicknesses, Radiation,Syndrome, Radiation,Syndromes, Radiation
D011879	Radiotherapy Dosage	The total amount of radiation absorbed by tissues as a result of radiotherapy.	Dosage, Radiotherapy,Dosages, Radiotherapy,Radiotherapy Dosages
D001918	Brachytherapy	A collective term for interstitial, intracavity, and surface radiotherapy. It uses small sealed or partly-sealed sources that may be placed on or near the body surface or within a natural body cavity or implanted directly into the tissues.	Curietherapy,Implant Radiotherapy,Plaque Therapy, Radioisotope,Radioisotope Brachytherapy,Radiotherapy, Interstitial,Radiotherapy, Intracavity,Radiotherapy, Surface,Brachytherapy, Radioisotope,Interstitial Radiotherapy,Intracavity Radiotherapy,Radioisotope Plaque Therapy,Radiotherapy, Implant,Surface Radiotherapy,Therapy, Radioisotope Plaque
D002142	Californium	A man-made radioactive actinide with atomic symbol Cf, atomic number 98, and atomic weight 251. Its valence can be +2 or +3. Californium has medical use as a radiation source for radiotherapy.
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly
D014059	Tongue	A muscular organ in the mouth that is covered with pink tissue called mucosa, tiny bumps called papillae, and thousands of taste buds. The tongue is anchored to the mouth and is vital for chewing, swallowing, and for speech.	Tongues
D014060	Tongue Diseases	Diseases involving the TONGUE.	Microglossia,Disease, Tongue,Diseases, Tongue,Microglossias,Tongue Disease