Biomaterial Database

The effect of pregnenolone, progesterone, deoxycorticosterone or corticosterone on the time of ovulation and oviposition in the hen. 1976

R J Etches, and F J Cunningham

Pregnenolone, progesterone, deoxycorticosterone and corticosterone were injected into hens between 16.30 and 17.00 h on the day of oviposition of the last egg of a sequence. 2. Pregnenolone did not affect ovulation, but all of the other steroids induced ovulation prematurely. 3. To induce premature ovulation in 50% of the hens, 82-31 mug+/-0-06 mug, 23-86 mug+/-0-07 mug and 659-26 mug+/-0-05 mug of progesterone, deoxycorticosterone and corticosterone, respectively were required for injection. 4. Differences were observed in the times of oviposition of eggs which ovulated in response to injections of either progesterone or a corticosteroid and it was suggested that the mechanism of action of progesterone and corticosteroids operates through different endocrine pathways.

UI	MeSH Term	Description	Entries
D010058	Oviposition	The process of laying or shedding fully developed eggs (OVA) from the female body. The term is usually used for certain INSECTS or FISHES with an organ called ovipositor where eggs are stored or deposited before expulsion from the body.	Larviposition,Larvipositions,Ovipositions
D010060	Ovulation	The discharge of an OVUM from a rupturing follicle in the OVARY.	Ovulations
D011284	Pregnenolone	A 21-carbon steroid, derived from CHOLESTEROL and found in steroid hormone-producing tissues. Pregnenolone is the precursor to GONADAL STEROID HORMONES and the adrenal CORTICOSTEROIDS.	5-Pregnen-3-beta-ol-20-one,5 Pregnen 3 beta ol 20 one
D011374	Progesterone	The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS.	Pregnenedione,Progesterone, (13 alpha,17 alpha)-(+-)-Isomer,Progesterone, (17 alpha)-Isomer,Progesterone, (9 beta,10 alpha)-Isomer
D002645	Chickens	Common name for the species Gallus gallus, the domestic fowl, in the family Phasianidae, order GALLIFORMES. It is descended from the red jungle fowl of SOUTHEAST ASIA.	Gallus gallus,Gallus domesticus,Gallus gallus domesticus,Chicken
D003345	Corticosterone	An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)
D003900	Desoxycorticosterone	A steroid metabolite that is the 11-deoxy derivative of CORTICOSTERONE and the 21-hydroxy derivative of PROGESTERONE	21-Hydroxyprogesterone,Cortexone,Deoxycorticosterone,Desoxycortone,11-Decorticosterone,21-Hydroxy-4-pregnene-3,20-dione,11 Decorticosterone,21 Hydroxy 4 pregnene 3,20 dione,21 Hydroxyprogesterone
D005260	Female		Females
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor