[Exposure of recovery room personnel to inhalation anesthetics]. 1998

K Westphal, and C Byhahn, and U Strouhal, and H J Wilke, and V Lischke, and M Behne
Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Johann Wolfgang Goethe-Universität Frankfurt/Main.

Both desflurane and sevoflurane have a favourable blood/gas distribution coefficient. There is concern, however, that environmental contamination is higher when these agents are employed since they must be used in relatively high concentrations. Our study seeks to determine the degree of exposure of recovery room staff to trace amounts of these two agents. Two hundred and seven surgical patients were included in the study. The recovery room studied had a volume of 243 cubic metres. The hourly fresh air supply for this room was 1,845 cubic metres, which results in 7.6 air exchanges per hour without air return. Measurements of trace concentrations of the inhalational agents were taken for 12 days. Concentrations of these anaesthetics were assessed in the recovery room with a real-time infrared spectrometer every 90 seconds. Mean exposure to nitrous oxide in the recovery room was 11.5 +/- 3.97 ppm and to isoflurane 1.4 +/- 0.31 ppm. All measured values were below the standard German threshold values. Trace concentrations of desflurane were 2.8 +/- 0.84 ppm and of sevoflurane 3.2 +/- 0.62 ppm. We conclude that the exposure to the inhalational anaesthetics in the climatised recovery room was low. The threshold values of 100 ppm for nitrous oxide and 10 ppm for isoflurane recommended by German law were not exceeded. When the new volatile anaesthetics are used, exposure of recovery room staff to trace concentrations of these agents is higher, but the concentrations do not exceed the levels allowed applicable German health regulations.

UI MeSH Term Description Entries
D007530 Isoflurane A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
D008738 Methyl Ethers A group of compounds that contain the general formula R-OCH3. Ethers, Methyl
D009609 Nitrous Oxide Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream. Laughing Gas,Nitrogen Protoxide,Gas, Laughing,Oxide, Nitrous
D004784 Environmental Monitoring The monitoring of the level of toxins, chemical pollutants, microbial contaminants, or other harmful substances in the environment (soil, air, and water), workplace, or in the bodies of people and animals present in that environment. Monitoring, Environmental,Environmental Surveillance,Surveillance, Environmental
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000077149 Sevoflurane A non-explosive inhalation anesthetic used in the induction and maintenance of general anesthesia. It does not cause respiratory irritation and may also prevent PLATELET AGGREGATION. BAX 3084,Fluoromethyl Hexafluoroisopropyl Ether,Fluoromethyl-2,2,2-trifluoro-1-(trifluoromethyl)ethyl Ether,Sevorane,Ultane
D000077335 Desflurane A fluorinated ether that is used as a volatile anesthetic for maintenance of general anesthesia. 1,2,2,2-Tetrafluoroethyl difluoromethyl ether,I 653,I-653,I653,Suprane
D000395 Air Pollutants, Occupational Toxic air-borne matter related to work performed They are usually produced by the specific nature of the occupation. Occupational Air Pollutants,Pollutants, Occupational Air
D000762 Anesthesia Recovery Period The period of emergence from general anesthesia, where different elements of consciousness return at different rates. Recovery Period, Anesthesia,Anesthesia Recovery Periods,Period, Anesthesia Recovery,Periods, Anesthesia Recovery,Recovery Periods, Anesthesia
D012307 Risk Factors An aspect of personal behavior or lifestyle, environmental exposure, inborn or inherited characteristic, which, based on epidemiological evidence, is known to be associated with a health-related condition considered important to prevent. Health Correlates,Risk Factor Scores,Risk Scores,Social Risk Factors,Population at Risk,Populations at Risk,Correlates, Health,Factor, Risk,Factor, Social Risk,Factors, Social Risk,Risk Factor,Risk Factor Score,Risk Factor, Social,Risk Factors, Social,Risk Score,Score, Risk,Score, Risk Factor,Social Risk Factor

Related Publications

K Westphal, and C Byhahn, and U Strouhal, and H J Wilke, and V Lischke, and M Behne
March 1987, Ma zui xue za zhi = Anaesthesiologica Sinica,
K Westphal, and C Byhahn, and U Strouhal, and H J Wilke, and V Lischke, and M Behne
January 1977, Anesthesia and analgesia,
K Westphal, and C Byhahn, and U Strouhal, and H J Wilke, and V Lischke, and M Behne
December 1987, Zeitschrift fur die gesamte Hygiene und ihre Grenzgebiete,
K Westphal, and C Byhahn, and U Strouhal, and H J Wilke, and V Lischke, and M Behne
December 1992, Minerva anestesiologica,
K Westphal, and C Byhahn, and U Strouhal, and H J Wilke, and V Lischke, and M Behne
March 1999, Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)),
K Westphal, and C Byhahn, and U Strouhal, and H J Wilke, and V Lischke, and M Behne
January 1981, International anesthesiology clinics,
K Westphal, and C Byhahn, and U Strouhal, and H J Wilke, and V Lischke, and M Behne
August 1995, Der Anaesthesist,
K Westphal, and C Byhahn, and U Strouhal, and H J Wilke, and V Lischke, and M Behne
January 2023, Environmental science and pollution research international,
K Westphal, and C Byhahn, and U Strouhal, and H J Wilke, and V Lischke, and M Behne
January 2000, Giornale italiano di medicina del lavoro ed ergonomia,
K Westphal, and C Byhahn, and U Strouhal, and H J Wilke, and V Lischke, and M Behne
January 1976, Revista de chirurgie, oncologie, radiologie, o.r.l., oftalmologie, stomatologie. Chirurgie,
Copied contents to your clipboard!