Biomaterial Database

[Biocompatibility of flexible intraocular lenses in vivo]. 1999

M Wenzel, and S Langefeld, and T von Fischern, and N Schrage

Augenklinik der RWTH, Aachen.

OBJECTIVE One aspect of biocompatibility of IOLs can be tested using specular microscopy of the anterior and posterior surface of the lens in vivo. METHODS We examined 45 patients after implantation of a "Memory lens" and 31 patients after the implantation of an "Acrysof" lens 3-6 months after surgery. RESULTS Typical deposits (Lens epithelial cells, spindle-shaped macrophages, giant cells, pigment, Wolter membrane) were rarely seen on both types of lenses. There were fewer lens epithelial cells on the posterior capsule and less secondary cataract after implantation of the "Acrysof" lens. CONCLUSIONS We did not find any indication of reduced biocompatibility in any of the lenses examined. The reduced rate of secondary cataract after implantation of the "memory lens" may be explained by the fact that this lens type sticks to the posterior capsule better.

UI	MeSH Term	Description	Entries
D007910	Lenses, Intraocular	Artificial implanted lenses.	Implantable Contact Lens,Lens, Intraocular,Contact Lens, Implantable,Intraocular Lens,Intraocular Lenses,Lens, Implantable Contact
D008297	Male		Males
D008422	Materials Testing	The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility.	Biocompatibility Testing,Biocompatible Materials Testing,Hemocompatibility Testing,Testing, Biocompatible Materials,Testing, Hemocompatible Materials,Hemocompatibility Testings,Hemocompatible Materials Testing,Materials Testing, Biocompatible,Materials Testing, Hemocompatible,Testing, Biocompatibility,Testing, Hemocompatibility,Testing, Materials,Testings, Biocompatibility
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly
D013499	Surface Properties	Characteristics or attributes of the outer boundaries of objects, including molecules.	Properties, Surface,Property, Surface,Surface Property
D019544	Equipment Failure Analysis	The evaluation of incidents involving the loss of function of a device. These evaluations are used for a variety of purposes such as to determine the failure rates, the causes of failures, costs of failures, and the reliability and maintainability of devices.	Materials Failure Analysis,Prosthesis Failure Analysis,Analysis, Equipment Failure,Analysis, Materials Failure,Analysis, Prosthesis Failure,Analyses, Equipment Failure,Analyses, Materials Failure,Analyses, Prosthesis Failure,Equipment Failure Analyses,Failure Analyses, Equipment,Failure Analyses, Materials,Failure Analyses, Prosthesis,Failure Analysis, Equipment,Failure Analysis, Materials,Failure Analysis, Prosthesis,Materials Failure Analyses,Prosthesis Failure Analyses