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This paper investigates the prognostic value of flash visual evoked potentials (VEPs) recorded in preterm infants at birth and at term age with respect to severe neurological outcome. Flash VEPs were recorded in 81 preterm infants at birth (i.e. <35 weeks' gestation) and repeated in 56 of these infants at term age. The preterm infants were assigned to either a healthy or at-risk subgroup based on clinical birth factors. Normal ranges of flash-VEP latencies, amplitudes, and number of components present were obtained from the subgroup of healthy preterm infants and from 68 term infants tested postnatally. The flash-VEP results of the entire preterm group were compared with the normal ranges and any abnormalities noted. Seven preterm infants in the at-risk group died, six of whom had abnormal flash VEPs before term age. Of the five infants from the at-risk group diagnosed with cerebral palsy (CP), three had abnormal flash VEPs before term age. Thus the sensitivity and specificity of the flash VEP with respect to survival was 86% and 89% respectively, and with respect to the development of CP was 60% and 92%. The abnormal features of the flash VEP associated with adverse outcomes comprised a delayed N3 component before term age and the absence of a positive component (P2) at term age.
A J Shepherd, and
K J Saunders, and
D L McCulloch, and
G N Dutton
March 2013,
Ophthalmology,
A J Shepherd, and
K J Saunders, and
D L McCulloch, and
G N Dutton
January 1998,
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A J Shepherd, and
K J Saunders, and
D L McCulloch, and
G N Dutton
January 2024,
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A J Shepherd, and
K J Saunders, and
D L McCulloch, and
G N Dutton
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A J Shepherd, and
K J Saunders, and
D L McCulloch, and
G N Dutton
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A J Shepherd, and
K J Saunders, and
D L McCulloch, and
G N Dutton
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Zhonghua yi xue za zhi,
A J Shepherd, and
K J Saunders, and
D L McCulloch, and
G N Dutton
January 1994,
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A J Shepherd, and
K J Saunders, and
D L McCulloch, and
G N Dutton
May 1989,
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A J Shepherd, and
K J Saunders, and
D L McCulloch, and
G N Dutton
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Early human development,
A J Shepherd, and
K J Saunders, and
D L McCulloch, and
G N Dutton
January 1994,
European journal of ophthalmology,
