-transparent.png){kind=logo}
In order to reveal and characterise genetic events occurring in renal tumorigenesis, samples of sporadic renal cell carcinomas (RCCs) were examined using restriction landmark genomic scanning (RLGS), an electrophoretic separation technique which detects gene amplification and deletion. We were able to find two fragments frequently amplified and 10 others commonly showing reduced signal intensity within the 16 tumour samples analysed. These altered spots were located on chromosomes 2, 3, 9-12, 16, 17 and 18 according to chromosomal assigned RLGS. A subset of reduced fragments appeared to be correlated to tumour type and were located within a new chromosomal region, suggesting genetic specificity within the process of renal carcinogenesis.
M Cho, and
N Konishi, and
K Yamamoto, and
T Inui, and
Y Kitahori, and
Y Nakagawa, and
H Uemura, and
Y Hirao, and
Y Hiasa
March 1999,
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology,
M Cho, and
N Konishi, and
K Yamamoto, and
T Inui, and
Y Kitahori, and
Y Nakagawa, and
H Uemura, and
Y Hirao, and
Y Hiasa
December 1997,
International journal of oncology,
M Cho, and
N Konishi, and
K Yamamoto, and
T Inui, and
Y Kitahori, and
Y Nakagawa, and
H Uemura, and
Y Hirao, and
Y Hiasa
September 1997,
Journal of neuro-oncology,
M Cho, and
N Konishi, and
K Yamamoto, and
T Inui, and
Y Kitahori, and
Y Nakagawa, and
H Uemura, and
Y Hirao, and
Y Hiasa
January 1997,
The American journal of pathology,
M Cho, and
N Konishi, and
K Yamamoto, and
T Inui, and
Y Kitahori, and
Y Nakagawa, and
H Uemura, and
Y Hirao, and
Y Hiasa
January 1997,
Brain tumor pathology,
M Cho, and
N Konishi, and
K Yamamoto, and
T Inui, and
Y Kitahori, and
Y Nakagawa, and
H Uemura, and
Y Hirao, and
Y Hiasa
July 2000,
Journal of hepatology,
M Cho, and
N Konishi, and
K Yamamoto, and
T Inui, and
Y Kitahori, and
Y Nakagawa, and
H Uemura, and
Y Hirao, and
Y Hiasa
January 1993,
Cancer detection and prevention,
M Cho, and
N Konishi, and
K Yamamoto, and
T Inui, and
Y Kitahori, and
Y Nakagawa, and
H Uemura, and
Y Hirao, and
Y Hiasa
January 1998,
Brain tumor pathology,
M Cho, and
N Konishi, and
K Yamamoto, and
T Inui, and
Y Kitahori, and
Y Nakagawa, and
H Uemura, and
Y Hirao, and
Y Hiasa
January 2006,
Nature protocols,
M Cho, and
N Konishi, and
K Yamamoto, and
T Inui, and
Y Kitahori, and
Y Nakagawa, and
H Uemura, and
Y Hirao, and
Y Hiasa
February 1993,
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme,
