The authors discuss the progress of acute myocardial infarction in a male subject, aged 39 suffering multiple sclerosis for 11 years. The progress of the infarction is severe but with a favourable outcome. It comes to confirm the literature survey of the existence of a correlation between the neurologic disturbance with the accompanying disturbances in lipid, protein and carbohydrate metabolism, increased blood coagulation ability and the ischemic heart disease. The incidence (10%) of multiple sclerosis among the neurologic diseases of organic nature and the affect of people in their most productive age (20-40) and the mutual relationship with the ischemic heart disease brings for the necessity of a early detection and treatment of the present coronary insufficiency, parallelly with the basic disease, in order to improve the prognosis of those patients.