Poor outcome in patients aged over 80 with limb-threatening ischaemia. 1999

B Davies, and B P Heather, and J J Earnshaw
Gloucestershire Royal Hospital, Gloucester, UK.

The aim of this study was to determine the outcome in a consecutive series of patients over 80 years of age with limb-threatening ischaemia. The authors performed a retrospective case-note review of the treatment and outcome in 108 patients with 131 episodes of leg ischaemia, who presented to a vascular unit between 1992-1996 inclusively. Some 73 (56%) episodes of leg ischaemia occurred in patients suitable for active treatment (limb salvage 75%, amputation 4% and death 21%). Results were inferior in patients not actively treated (limb salvage 19%, amputation 50% and death 31%). Elderly patients not selected for active treatment have a very poor outcome and are seldom mentioned in publications. In future, clinical reports should include actively treated and rejected patients to avoid selection bias. Research should focus on the selection process and alternative therapies.

UI MeSH Term Description Entries
D007511 Ischemia A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION. Ischemias
D007866 Leg The inferior part of the lower extremity between the KNEE and the ANKLE. Legs
D008297 Male Males
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D000369 Aged, 80 and over Persons 80 years of age and older. Oldest Old
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective
D016896 Treatment Outcome Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series. Rehabilitation Outcome,Treatment Effectiveness,Clinical Effectiveness,Clinical Efficacy,Patient-Relevant Outcome,Treatment Efficacy,Effectiveness, Clinical,Effectiveness, Treatment,Efficacy, Clinical,Efficacy, Treatment,Outcome, Patient-Relevant,Outcome, Rehabilitation,Outcome, Treatment,Outcomes, Patient-Relevant,Patient Relevant Outcome,Patient-Relevant Outcomes

Related Publications

B Davies, and B P Heather, and J J Earnshaw
October 1995, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery,
B Davies, and B P Heather, and J J Earnshaw
January 2018, BMJ (Clinical research ed.),
B Davies, and B P Heather, and J J Earnshaw
November 2021, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery,
B Davies, and B P Heather, and J J Earnshaw
July 2022, The British journal of surgery,
B Davies, and B P Heather, and J J Earnshaw
February 2021, Medicine,
B Davies, and B P Heather, and J J Earnshaw
October 1995, The British journal of surgery,
B Davies, and B P Heather, and J J Earnshaw
December 2012, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery,
B Davies, and B P Heather, and J J Earnshaw
August 2015, The British journal of surgery,
B Davies, and B P Heather, and J J Earnshaw
August 2021, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery,
B Davies, and B P Heather, and J J Earnshaw
March 2023, The British journal of surgery,
Copied contents to your clipboard!