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Inactivated hepatitis A virus (HAV) vaccine was administered to 55 healthy seronegative adult volunteers to evaluate the immunogenicity and adverse reactions of two doses of HAV vaccination (25 units) in comparison with a three-dose regimen. The volunteers were randomly assigned to receive one of the two regimens: 26 were vaccinated with two doses at 0 and 24 weeks (Group 1), and 29 were vaccinated with three doses at 0, 2, and 24 weeks (Group 2). The vaccine was well tolerated and there was no serious adverse reaction. In both groups, the seroconversion rate was 100% at week 28. At week 52, all remained positive for anti-HAV regardless of a two- or three-dose regimen. No statistically significant difference in seroconversion rates and geometric mean titers could be demonstrated between the two groups. Thus, the two-dose regimen may be favorable to save cost and time for active immunization against hepatitis A.
M Y Lu, and
M H Chang, and
K S Tsai, and
D S Chen
January 1998,
Asian Pacific journal of allergy and immunology,
M Y Lu, and
M H Chang, and
K S Tsai, and
D S Chen
January 1992,
Vaccine,
M Y Lu, and
M H Chang, and
K S Tsai, and
D S Chen
January 1999,
The National medical journal of India,
M Y Lu, and
M H Chang, and
K S Tsai, and
D S Chen
January 1999,
Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi,
M Y Lu, and
M H Chang, and
K S Tsai, and
D S Chen
August 2010,
Vaccine,
M Y Lu, and
M H Chang, and
K S Tsai, and
D S Chen
December 2000,
Vaccine,
M Y Lu, and
M H Chang, and
K S Tsai, and
D S Chen
September 2022,
Vaccine,
M Y Lu, and
M H Chang, and
K S Tsai, and
D S Chen
October 1996,
Vaccine,
M Y Lu, and
M H Chang, and
K S Tsai, and
D S Chen
June 2002,
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases,
M Y Lu, and
M H Chang, and
K S Tsai, and
D S Chen
July 2004,
Clinical therapeutics,
