-transparent.png){kind=logo}
From April 1971 to September 1977, 94 children with acute lymphocytic leukemia, in whom a complete clinical and hematologic remission had been obtained received preventive cranial irradiation at the University Clinic for Radiotherapy of Vienna. So far, only in 2 of the 94 patients an initial meningeal relapse occurred. After a minimum follow-up time of 3 years, the rate of primary CNS relapse is 8%. The combination of cranial irradiation and methotrexate intrathecally, beginning currently in the first month of the complete remission, seems to be the most effective and least hazardous regimen to prevent meningeal and CNS leukemia.
Related Publications
G Reinartz, and
H D Kogelnik, and
P Krepler, and
W Schmidmeier, and
E Pichler
May 1978,
The Journal of pediatrics,
G Reinartz, and
H D Kogelnik, and
P Krepler, and
W Schmidmeier, and
E Pichler
January 1976,
Strahlentherapie,
G Reinartz, and
H D Kogelnik, and
P Krepler, and
W Schmidmeier, and
E Pichler
January 1983,
American journal of diseases of children (1960),
G Reinartz, and
H D Kogelnik, and
P Krepler, and
W Schmidmeier, and
E Pichler
March 1983,
The New England journal of medicine,
G Reinartz, and
H D Kogelnik, and
P Krepler, and
W Schmidmeier, and
E Pichler
November 2003,
Pediatric neurosurgery,
G Reinartz, and
H D Kogelnik, and
P Krepler, and
W Schmidmeier, and
E Pichler
February 1981,
The Journal of pediatrics,
G Reinartz, and
H D Kogelnik, and
P Krepler, and
W Schmidmeier, and
E Pichler
March 1980,
The Journal of pediatrics,
G Reinartz, and
H D Kogelnik, and
P Krepler, and
W Schmidmeier, and
E Pichler
November 1979,
Acta paediatrica Scandinavica,
G Reinartz, and
H D Kogelnik, and
P Krepler, and
W Schmidmeier, and
E Pichler
March 1979,
International journal of radiation oncology, biology, physics,
G Reinartz, and
H D Kogelnik, and
P Krepler, and
W Schmidmeier, and
E Pichler
October 1984,
Journal of neurosurgery,
