Biomaterial Database

[Effect of fat on renal water excretion under conditions of disorders in the secretion of antidiuretic hormone]. 1976

Iu O Abel'son

The fat antidiuretic effect was studied in rats with inhereted diabetes insipidus (DI rats). In these animals the decrease of urine flow after fat ingestion was less stable and less profound as compared with non--DI: sunflower oil produced no effect in 12 DI rats out of 19, the per cent of inhibition in the other 7 being not more than 50%. No changes in urine osmalality were observed during the period of fat inhibition, while a significant decrease in creatinine excretion was revealed. Fat antidiuresis in DI rats was not affected by ethanol administration. These findings corroborate the assumption that fat ingestion in healthy animals is accompanied by the ADH release. It seems that changes in glomerular filtration rate are involved in the mechanism of this kind of antidiuretic response, at least in rats with impaired ADH secretion

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009821	Oils	Unctuous combustible substances that are liquid or easily liquefiable on warming, and are soluble in ether but insoluble in water. Such substances, depending on their origin, are classified as animal, mineral, or vegetable oils. Depending on their behavior on heating, they are volatile or fixed. (Dorland, 28th ed)
D009994	Osmolar Concentration	The concentration of osmotically active particles in solution expressed in terms of osmoles of solute per liter of solution. Osmolality is expressed in terms of osmoles of solute per kilogram of solvent.	Ionic Strength,Osmolality,Osmolarity,Concentration, Osmolar,Concentrations, Osmolar,Ionic Strengths,Osmolalities,Osmolar Concentrations,Osmolarities,Strength, Ionic,Strengths, Ionic
D003404	Creatinine		Creatinine Sulfate Salt,Krebiozen,Salt, Creatinine Sulfate,Sulfate Salt, Creatinine
D003919	Diabetes Insipidus	A disease that is characterized by frequent urination, excretion of large amounts of dilute URINE, and excessive THIRST. Etiologies of diabetes insipidus include deficiency of antidiuretic hormone (also known as ADH or VASOPRESSIN) secreted by the NEUROHYPOPHYSIS, impaired KIDNEY response to ADH, and impaired hypothalamic regulation of thirst.
D004231	Diuresis	An increase in the excretion of URINE. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)	Diureses
D005260	Female		Females
D006368	Helianthus	A genus herbs of the Asteraceae family. The SEEDS yield oil and are used as food and animal feed; the roots of Helianthus tuberosum (Jerusalem artichoke) are edible.	Jerusalem Artichoke,Sunflower,Helianthus annuus,Helianthus tuberosus,Artichoke, Jerusalem,Sunflowers
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D051381	Rats	The common name for the genus Rattus.	Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus