Biomaterial Database

[Immunodiffusion and immunoelectrophoretic techniques applied to psoriasis (author's transl)]. 1978

M A Bertrand, and C Ormières, and J Bazex, and J Breuillaud, and A Bazex

Serum and scales of skin obtained from normal and psoriatic subjects are tested and estimated by immune diffusion and immune electrophoresis technics. The authors relate technics to produce rabbit's antibodies towards psoriatic serums and extracts of skin. Results coroborate the quantitative modifications of immunoglobulins and show in addition the presence of multiple precipitations lines in the alpha and gamma regions. Lastly, in psoriatic scales a globulin is found, which is not present in normal scales or normal serums.

UI	MeSH Term	Description	Entries
D007122	Immunoelectrophoresis	A technique that combines protein electrophoresis and double immunodiffusion. In this procedure proteins are first separated by gel electrophoresis (usually agarose), then made visible by immunodiffusion of specific antibodies. A distinct elliptical precipitin arc results for each protein detectable by the antisera.
D011565	Psoriasis	A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis.	Palmoplantaris Pustulosis,Pustular Psoriasis of Palms and Soles,Pustulosis Palmaris et Plantaris,Pustulosis of Palms and Soles,Psoriases
D005779	Immunodiffusion	Technique involving the diffusion of antigen or antibody through a semisolid medium, usually agar or agarose gel, with the result being a precipitin reaction.	Gel Diffusion Tests,Diffusion Test, Gel,Diffusion Tests, Gel,Gel Diffusion Test,Immunodiffusions,Test, Gel Diffusion,Tests, Gel Diffusion
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man