Biomaterial Database

Complications of mechanical ventilation in a children's hospital multidisciplinary intensive care unit. 1990

P K Benjamin, and J E Thompson, and P P O'Rourke

Children's Hospital, Boston MA 02115.

During a 12-week period, 204 consecutive patients admitted to the multidisciplinary intensive-care unit of a children's hospital were prospectively studied for complications of mechanical ventilation. METHODS A respiratory therapist completed a standardized data form at the end of each shift for each ventilated patient. Patient age, sex, length of ventilation, diagnosis, and complications were noted. Complications were classified as relating to the endotracheal tube (ETT), the ventilator, or the patient's medical management, and were analyzed according to incidence (number per 100 patients or per 100 ventilator days) and to associated mortality. RESULTS Patients ranged in age from newborn to 24 years. Sixty-three percent were male. Twenty-one percent of patients were managed by the medical staff, 11% by the general surgical staff, and 68% by the cardiac surgical staff. Average length of ventilation was 5.2 days. Overall survival rate was 91.7%. ETT complications reported as number per 100 patients were: pre-necrosis (13.0 [4/57 orally intubated patients and 23/147 nasally intubated patients]), ETT retaping complications (6.0), ETT plugging (1.0), and self-extubation (3.0). Ventilator complications reported as number per 100 ventilator days were: alarm failures (6.5), ventilator failures (0.7), and circuit problems (7.0). Medical complications reported as number per 100 patients were: massive gastric distension (8.8), right-upper-lobe collapse (4.4), pneumothorax (4.4), subcutaneous air (1.5), and pneumoperitoneum (1.0). ETT and ventilator complications showed no association with mortality. The large number of cardiac infants less than 24 months of age (n = 101) led us to further analyze this group for survival rate. We found that the survival rate was 93% for those requiring less than 7 days mechanical ventilation and 89.3% for those requiring greater than or equal to 7 days. As the study progressed, the respiratory therapists independently noted that their attentiveness to both patient and machine increased as did their awareness of complications. The incidence of alarm failure, circuit problems, and pre-necrosis was higher among the first 103 patients compared to the 101 patients entered into the study subsequently.

UI	MeSH Term	Description	Entries
D007223	Infant	A child between 1 and 23 months of age.	Infants
D007231	Infant, Newborn	An infant during the first 28 days after birth.	Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D012122	Ventilators, Mechanical	Mechanical devices used to produce or assist pulmonary ventilation.	Mechanical Ventilator,Mechanical Ventilators,Respirators,Ventilators, Pulmonary,Pulmonary Ventilator,Pulmonary Ventilators,Ventilator, Pulmonary,Ventilators,Respirator,Ventilator,Ventilator, Mechanical
D012138	Respiratory Therapy	Care of patients with deficiencies and abnormalities associated with the cardiopulmonary system. It includes the therapeutic use of medical gases and their administrative apparatus, environmental control systems, humidification, aerosols, ventilatory support, bronchopulmonary drainage and exercise, respiratory rehabilitation, assistance with cardiopulmonary resuscitation, and maintenance of natural, artificial, and mechanical airways.	Inhalation Therapy,Therapy, Inhalation,Therapy, Respiratory,Inhalation Therapies,Respiratory Therapies,Therapies, Inhalation,Therapies, Respiratory
D001900	Boston	City located in Massachusetts.
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D003625	Data Collection	Systematic gathering of data for a particular purpose from various sources, including questionnaires, interviews, observation, existing records, and electronic devices. The process is usually preliminary to statistical analysis of the data.	Data Collection Methods,Dual Data Collection,Collection Method, Data,Collection Methods, Data,Collection, Data,Collection, Dual Data,Data Collection Method,Method, Data Collection,Methods, Data Collection
D004868	Equipment Failure	Failure of equipment to perform to standard. The failure may be due to defects or improper use.	Defects, Equipment,Device Failure,Failure, Equipment,Malfunction, Equipment,Medical Device Failure,Misuse, Equipment,Device Failure, Medical,Device Failures, Medical,Failure, Medical Device,Failures, Medical Device,Defect, Equipment,Device Failures,Equipment Defect,Equipment Defects,Equipment Failures,Equipment Malfunction,Equipment Malfunctions,Equipment Misuse,Equipment Misuses,Failure, Device,Failures, Device,Failures, Equipment,Malfunctions, Equipment,Misuses, Equipment
D005069	Evaluation Studies as Topic	Works about studies that determine the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies.	Critique,Evaluation Indexes,Evaluation Methodology,Evaluation Report,Evaluation Research,Methodology, Evaluation,Pre-Post Tests,Qualitative Evaluation,Quantitative Evaluation,Theoretical Effectiveness,Use-Effectiveness,Critiques,Effectiveness, Theoretical,Evaluation Methodologies,Evaluation Reports,Evaluation, Qualitative,Evaluation, Quantitative,Evaluations, Qualitative,Evaluations, Quantitative,Indexes, Evaluation,Methodologies, Evaluation,Pre Post Tests,Pre-Post Test,Qualitative Evaluations,Quantitative Evaluations,Report, Evaluation,Reports, Evaluation,Research, Evaluation,Test, Pre-Post,Tests, Pre-Post,Use Effectiveness