Color Doppler determination of regurgitant flow: from proximal isovelocity surface areas to proximal velocity profiles. An in vitro study. 1992

M O Giesler, and M Stauch
Division of Sports Medicine, Internal Medicine, University of Ulm, Federal Republic of Germany.

There is not yet a completely satisfactory Doppler method for determining the severity of valvular regurgitation. Recently, interest has focused on the so-called "flow convergence region." Color Doppler provides a longitudinal velocity profile of the flow convergence region proximal to restrictive orifices. With respect to determination of regurgitant flow rate, we studied the influence of orifice flow rate and orifice size on the proximal velocity profile. In a phantom model, flow across circular orifices was studied. The distance r (v) of discrete velocities detected proximal to the orifice was measured along the flow center line. Velocity profiles were established. (1) Proximal isovelocity surfaces: The radius r (v) also represented the central radius of the proximal isovelocity surfaces. Increases in flow resulted in larger central radii r (v). Application of the continuity equation and analysis of the resulting values yielded a radius and an orifice size dependence of the geometric isovelocity surface shape. Therefore, their surface area and flow rate could not be calculated from these axial measurements alone. (2) Proximal velocity profiles: The resulting hyperbolic velocity profile curves (x axis = velocity [v], y axis = distance [r (v)]) are shifted rightward by increases in flow. In contrast, increases in orifice size make the curve steeper, but large r (v) are not affected. This differential influence of flow rate and orifice size allows orifice size independent determination of flow rate. A nomogram is presented as one possible method for flow determination.

UI MeSH Term Description Entries
D008955 Models, Cardiovascular Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment. Cardiovascular Model,Cardiovascular Models,Model, Cardiovascular
D008961 Models, Structural A representation, generally small in scale, to show the structure, construction, or appearance of something. (From Random House Unabridged Dictionary, 2d ed) Model, Structural,Structural Model,Structural Models
D001775 Blood Circulation The movement of the BLOOD as it is pumped through the CARDIOVASCULAR SYSTEM. Blood Flow,Circulation, Blood,Blood Flows,Flow, Blood
D001783 Blood Flow Velocity A value equal to the total volume flow divided by the cross-sectional area of the vascular bed. Blood Flow Velocities,Flow Velocities, Blood,Flow Velocity, Blood,Velocities, Blood Flow,Velocity, Blood Flow
D006349 Heart Valve Diseases Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE). Heart Valvular Disease,Valvular Heart Diseases,Disease, Heart Valvular,Heart Disease, Valvular,Heart Valve Disease,Heart Valvular Diseases,Valve Disease, Heart,Valvular Disease, Heart,Valvular Heart Disease
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D015150 Echocardiography, Doppler Measurement of intracardiac blood flow using an M-mode and/or two-dimensional (2-D) echocardiogram while simultaneously recording the spectrum of the audible Doppler signal (e.g., velocity, direction, amplitude, intensity, timing) reflected from the moving column of red blood cells. Doppler Echocardiography,Echocardiography, Continuous Doppler,Echocardiography, Two-Dimensional Doppler,2-D Doppler Echocardiography,2D Doppler Echocardiography,Continuous Doppler Echocardiography,Doppler Echocardiography, 2-D,Doppler Echocardiography, 2D,Doppler Echocardiography, Continuous,Doppler Echocardiography, Two-Dimensional,Echocardiography, 2-D Doppler,Echocardiography, 2D Doppler,Two-Dimensional Doppler Echocardiography,2 D Doppler Echocardiography,Doppler Echocardiography, 2 D,Doppler Echocardiography, Two Dimensional,Echocardiography, 2 D Doppler,Echocardiography, Two Dimensional Doppler,Two Dimensional Doppler Echocardiography

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