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OBJECTIVE The aim of this study was to assess whether non-invasive positive pressure ventilation delivered intermittently (Ni-IPPV) by means of a facial or nasal mask is beneficial in haematological patients suffering from acute respiratory failure. METHODS Prospective, open, non-randomised study. METHODS University Hospital, medical intensive care unit. METHODS Eighteen haematological patients with acute respiratory failure which occurred before, during or just after therapeutic aplasia were ventilated with Ni-IPPV delivered via an individual nasal mask or a standard facial mask. Non-invasive ventilation was achieved until weaning (success (S)) or intubation (failure (F)). RESULTS Twelve patients were ultimately intubated and died (F group). Seven needed intubation within 3 hours following admission because of the inability of Ni-IPPV to provide adequate ventilation in six patients and after cardiac arrest, probably related to cardiac aspergillosis in one patient. Six patients were not intubated and were discharged alive (S group). Of 11 patients who received Ni-IPPV for more than 3 hours, the respiratory rate decreased significantly (p < 0.05) from 33 +/- 7 breaths/min to 24 +/- 5 breaths/min with Ni-IPPV and the PaO2 increased significantly from 6.6 +/- 1.7 kPa upon admission to 17.7 +/- 5.5 kPa during Ni-IPPV. Mean daily ventilation was 12 +/- 7 hours for a mean duration of 5.5 +/- 4.4 days. Pressure support was used in nine patients and appeared the most efficient ventilation mode of non-invasive ventilation. The duration per day of Ni-IPPV was shorter and PaCO2 values during Ni-IPPV were lower in the S group than in the F group. CONCLUSIONS This technique is able to provide adequate ventilatory support for many haematological patients and allows avoidance of ventilation in some.
E Tognet, and
A Mercatello, and
P Polo, and
B Coronel, and
M Bret, and
E Archimbaud, and
J F Moskovtchenko
September 2002,
Emergency medicine (Fremantle, W.A.),
E Tognet, and
A Mercatello, and
P Polo, and
B Coronel, and
M Bret, and
E Archimbaud, and
J F Moskovtchenko
October 2000,
Minerva anestesiologica,
E Tognet, and
A Mercatello, and
P Polo, and
B Coronel, and
M Bret, and
E Archimbaud, and
J F Moskovtchenko
June 2005,
Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih,
E Tognet, and
A Mercatello, and
P Polo, and
B Coronel, and
M Bret, and
E Archimbaud, and
J F Moskovtchenko
October 2012,
Pediatric pulmonology,
E Tognet, and
A Mercatello, and
P Polo, and
B Coronel, and
M Bret, and
E Archimbaud, and
J F Moskovtchenko
February 2018,
Zhonghua wei zhong bing ji jiu yi xue,
E Tognet, and
A Mercatello, and
P Polo, and
B Coronel, and
M Bret, and
E Archimbaud, and
J F Moskovtchenko
November 2000,
Australian critical care : official journal of the Confederation of Australian Critical Care Nurses,
E Tognet, and
A Mercatello, and
P Polo, and
B Coronel, and
M Bret, and
E Archimbaud, and
J F Moskovtchenko
May 2006,
The Journal of the Association of Physicians of India,
E Tognet, and
A Mercatello, and
P Polo, and
B Coronel, and
M Bret, and
E Archimbaud, and
J F Moskovtchenko
October 2009,
Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue,
E Tognet, and
A Mercatello, and
P Polo, and
B Coronel, and
M Bret, and
E Archimbaud, and
J F Moskovtchenko
September 2011,
Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue,
E Tognet, and
A Mercatello, and
P Polo, and
B Coronel, and
M Bret, and
E Archimbaud, and
J F Moskovtchenko
May 2004,
Intensive care medicine,
