Biomaterial Database

Incidence of neomycin and framycetin sensitivity. 1976

J A Carruthers, and E Cronin

A total of 450 consecutive patients were patch-tested to both neomycin and framycetin (20% in petrolatum). Thirteen patients were sensitive to both preparations, 10 to neomycin alone and four to framycetin alone. The significance of these results is discussed, with particular reference to the constituents of the preparations and the allergenic groups involved.

UI	MeSH Term	Description	Entries
D009355	Neomycin	Aminoglycoside antibiotic complex produced by Streptomyces fradiae. It is composed of neomycins A, B, and C, and acts by inhibiting translation during protein synthesis.	Fradiomycin Sulfate,Neomycin Palmitate,Neomycin Sulfate
D010328	Patch Tests	Skin tests in which the sensitizer is applied to a patch of cotton cloth or gauze held in place for approximately 48-72 hours. It is used for the elicitation of a contact hypersensitivity reaction.	Patch Testing,Patch Test,Patch Testings,Test, Patch,Testing, Patch,Testings, Patch,Tests, Patch
D003877	Dermatitis, Contact	A type of acute or chronic skin reaction in which sensitivity is manifested by reactivity to materials or substances coming in contact with the skin. It may involve allergic or non-allergic mechanisms.	Contact Dermatitis,Dermatitis Venenata,Eczema, Contact,Hypersensitivity, Contact,Sensitivity, Contact,Contact Dermatitides,Contact Eczema,Contact Hypersensitivities,Contact Hypersensitivity,Contact Sensitivities,Contact Sensitivity,Dermatitides, Contact,Hypersensitivities, Contact,Sensitivities, Contact
D005601	Framycetin	A component of NEOMYCIN that is produced by Streptomyces fradiae. On hydrolysis it yields neamine and neobiosamine B. (From Merck Index, 11th ed)	Neomycin B,Antibiotic 10676,Framycetin Sulfate,Neomycin B Sulfate,Soframycin,Sulfate, Framycetin,Sulfate, Neomycin B
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man