Sarcogenesis essentially follows two laws: The frequency of sarcoma is distributed according to the mesenchymal cell content in the different sections of the body. The sites of predilection are found within the same tissue systems in zones of increased growth activity and cell division. Clinical oncogenic statistics show that other factors apart from quantity of sarcogenic noxae and latent period are important in producing the malignancy. The synopsis of histology, X-ray findings and clinical examination is significant for diagnosis and for prognosis the degree of spread (TNM classification), localization and therapy. Early operation is still the most successful and most decisive therapeutic measure. The necessity for a supervised cancer follow-up is also shown in these tumors.