Reciprocity between light intensity and rhodopsin concentration across the rat retina. 1999

T P Williams, and A Squitieri, and R P Henderson, and J P Webbers
Program in Neuroscience, The Florida State University, Tallahassee, FL 32306-4340, USA. tpw@neuro.fsu.edu

1. If a purpose of photostasis - absorption of a constant number of photons by the retina, regardless of incident light levels - is to maintain rods at saturation during the light period, then in retinal regions where light intensity is low, rhodopsin concentration should be high, and vice versa. 2. Our ocular transmission photometric measurements revealed that the distribution of light intensity across the rat retina was not as simple as had been thought and, furthermore, that the local concentration of rhodopsin had a high negative correlation with the light intensity. 3. The reciprocity between these two parameters leads to nearly uniform rates of photon absorption in rods across the retina.

UI MeSH Term Description Entries
D008027 Light That portion of the electromagnetic spectrum in the visible, ultraviolet, and infrared range. Light, Visible,Photoradiation,Radiation, Visible,Visible Radiation,Photoradiations,Radiations, Visible,Visible Light,Visible Radiations
D008297 Male Males
D010783 Photometry Measurement of the various properties of light. Photometries
D012160 Retina The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent. Ora Serrata
D005260 Female Females
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012243 Rhodopsin A purplish-red, light-sensitive pigment found in RETINAL ROD CELLS of most vertebrates. It is a complex consisting of a molecule of ROD OPSIN and a molecule of 11-cis retinal (RETINALDEHYDE). Rhodopsin exhibits peak absorption wavelength at about 500 nm. Visual Purple
D017207 Rats, Sprague-Dawley A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company. Holtzman Rat,Rats, Holtzman,Sprague-Dawley Rat,Rats, Sprague Dawley,Holtzman Rats,Rat, Holtzman,Rat, Sprague-Dawley,Sprague Dawley Rat,Sprague Dawley Rats,Sprague-Dawley Rats
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus
D017948 Retinal Rod Photoreceptor Cells Photosensitive afferent neurons located in the peripheral retina, with their density increases radially away from the FOVEA CENTRALIS. Being much more sensitive to light than the RETINAL CONE CELLS, the rod cells are responsible for twilight vision (at scotopic intensities) as well as peripheral vision, but provide no color discrimination. Photoreceptors, Rod,Retinal Rod Cells,Rod Photoreceptors,Rods (Retina),Retinal Rod,Retinal Rod Cell,Retinal Rod Photoreceptor,Retinal Rod Photoreceptors,Rod Photoreceptor Cells,Cell, Retinal Rod,Cell, Rod Photoreceptor,Cells, Retinal Rod,Cells, Rod Photoreceptor,Photoreceptor Cell, Rod,Photoreceptor Cells, Rod,Photoreceptor, Retinal Rod,Photoreceptor, Rod,Photoreceptors, Retinal Rod,Retinal Rods,Rod (Retina),Rod Cell, Retinal,Rod Cells, Retinal,Rod Photoreceptor,Rod Photoreceptor Cell,Rod Photoreceptor, Retinal,Rod Photoreceptors, Retinal,Rod, Retinal,Rods, Retinal

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