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This study has shown that lipofuscin pigment may accumulate in RPE cells and macrophages over several types of benign and malignant choroidal tumors. The color of the pigment, however, varies with the nature and color of the underlying lesion. On the surface of deeply pigmented tumors the lipofuscin pigment may produce an orange color, whereas over amelanotic lesions it may appear brown or reddish-brown. On the surface of vascular tumors, such as choroidal hemangiomas, the lipofuscin is almost invisible ophthalmoscopically but may be demonstrated with fluorescein angiography. Although the presence of such pigment accumulation is suggestive of a malignant melanoma, it is not diagnostic and may occur over benign simulating lesions as well.
J A Shields, and
M M Rodrigues, and
L K Sarin, and
W S Tasman, and
W H Annesley
April 1975,
Annals of ophthalmology,
J A Shields, and
M M Rodrigues, and
L K Sarin, and
W S Tasman, and
W H Annesley
August 1973,
American journal of ophthalmology,
J A Shields, and
M M Rodrigues, and
L K Sarin, and
W S Tasman, and
W H Annesley
January 1974,
Modern problems in ophthalmology,
J A Shields, and
M M Rodrigues, and
L K Sarin, and
W S Tasman, and
W H Annesley
June 1972,
American journal of ophthalmology,
J A Shields, and
M M Rodrigues, and
L K Sarin, and
W S Tasman, and
W H Annesley
August 2013,
JAMA ophthalmology,
J A Shields, and
M M Rodrigues, and
L K Sarin, and
W S Tasman, and
W H Annesley
February 1986,
Investigative ophthalmology & visual science,
J A Shields, and
M M Rodrigues, and
L K Sarin, and
W S Tasman, and
W H Annesley
December 1973,
Urological research,
J A Shields, and
M M Rodrigues, and
L K Sarin, and
W S Tasman, and
W H Annesley
June 1991,
Ophthalmology,
J A Shields, and
M M Rodrigues, and
L K Sarin, and
W S Tasman, and
W H Annesley
September 1987,
Clinical obstetrics and gynecology,
J A Shields, and
M M Rodrigues, and
L K Sarin, and
W S Tasman, and
W H Annesley
July 1993,
Nutrition reviews,
