-transparent.png){kind=logo}
Six healthy male volunteers were given chlorimipramine 25 mg t.i.d. or nortriptyline 25 mg t.i.d. in a randomized order of 7 days. Plasma samples were assayed for TSH, GH and prolactin before and after stimulation with TRH 200 microgram i.v. It was found that the tricyclic antidepressants did not exert any influence on plasma hormonal levels compared with no treatment conditions. Diminished TSH-responses following daily TRH injections were demonstrated in endogenously depressed and chronic schizophrenic patients. A decreased TSH-response was observed in healthy volunteers after a second TRH injection with an interval of 2 days between the TRH injections. A complete restoration of the TSH-response was obtained after an interval of 4 days.
E Widerlöv, and
L Wide, and
R Sjöström
June 2003,
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine,
E Widerlöv, and
L Wide, and
R Sjöström
July 1974,
Clinical pharmacology and therapeutics,
E Widerlöv, and
L Wide, and
R Sjöström
January 1977,
Psychopharmacology,
E Widerlöv, and
L Wide, and
R Sjöström
March 1981,
The Journal of the Kansas Medical Society,
E Widerlöv, and
L Wide, and
R Sjöström
September 1977,
Acta pharmacologica et toxicologica,
E Widerlöv, and
L Wide, and
R Sjöström
September 1990,
The American journal of psychiatry,
E Widerlöv, and
L Wide, and
R Sjöström
October 1976,
JAMA,
E Widerlöv, and
L Wide, and
R Sjöström
September 2001,
Journal of physiology and biochemistry,
E Widerlöv, and
L Wide, and
R Sjöström
January 1983,
International journal of psychiatry in medicine,
E Widerlöv, and
L Wide, and
R Sjöström
February 1992,
Journal of clinical psychopharmacology,
