Ventricular asystole during vagus nerve stimulation for epilepsy in humans. 1999

W O Tatum, and D B Moore, and M M Stecker, and G H Baltuch, and J A French, and J A Ferreira, and P M Carney, and D R Labar, and F L Vale
Department of Neurology, Tampa General Hospital, University of South Florida, USA. WOTIV@aol.com

Electrical stimulation of the vagus nerve, a recently available option for patients with refractory epilepsy, has demonstrated safety and efficacy. We report four patients with refractory epilepsy who experienced ventricular asystole intraoperatively during initial testing for implantation of the vagus nerve stimulator. Acute intraoperative vagus nerve stimulation may create ventricular asystole in humans. Extracorporeal cervical vagus nerve stimulation testing with continuous EKG monitoring intraoperatively before generator implantation is warranted.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D004827 Epilepsy A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313) Aura,Awakening Epilepsy,Seizure Disorder,Epilepsy, Cryptogenic,Auras,Cryptogenic Epilepsies,Cryptogenic Epilepsy,Epilepsies,Epilepsies, Cryptogenic,Epilepsy, Awakening,Seizure Disorders
D005260 Female Females
D006323 Heart Arrest Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation. Asystole,Cardiac Arrest,Cardiopulmonary Arrest,Arrest, Cardiac,Arrest, Cardiopulmonary,Arrest, Heart,Asystoles
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D014630 Vagus Nerve The 10th cranial nerve. The vagus is a mixed nerve which contains somatic afferents (from skin in back of the ear and the external auditory meatus), visceral afferents (from the pharynx, larynx, thorax, and abdomen), parasympathetic efferents (to the thorax and abdomen), and efferents to striated muscle (of the larynx and pharynx). Cranial Nerve X,Pneumogastric Nerve,Tenth Cranial Nerve,Nerve X,Nervus Vagus,Cranial Nerve, Tenth,Cranial Nerves, Tenth,Nerve X, Cranial,Nerve Xs,Nerve, Pneumogastric,Nerve, Tenth Cranial,Nerve, Vagus,Nerves, Pneumogastric,Nerves, Tenth Cranial,Nerves, Vagus,Pneumogastric Nerves,Tenth Cranial Nerves,Vagus Nerves,Vagus, Nervus
D016276 Ventricular Function The hemodynamic and electrophysiological action of the HEART VENTRICLES. Function, Ventricular,Functions, Ventricular,Ventricular Functions

Related Publications

W O Tatum, and D B Moore, and M M Stecker, and G H Baltuch, and J A French, and J A Ferreira, and P M Carney, and D R Labar, and F L Vale
February 2000, Neurology,
W O Tatum, and D B Moore, and M M Stecker, and G H Baltuch, and J A French, and J A Ferreira, and P M Carney, and D R Labar, and F L Vale
February 2000, Neurology,
W O Tatum, and D B Moore, and M M Stecker, and G H Baltuch, and J A French, and J A Ferreira, and P M Carney, and D R Labar, and F L Vale
October 2004, Epilepsy & behavior : E&B,
W O Tatum, and D B Moore, and M M Stecker, and G H Baltuch, and J A French, and J A Ferreira, and P M Carney, and D R Labar, and F L Vale
April 2009, Epilepsia,
W O Tatum, and D B Moore, and M M Stecker, and G H Baltuch, and J A French, and J A Ferreira, and P M Carney, and D R Labar, and F L Vale
December 2009, Epilepsia,
W O Tatum, and D B Moore, and M M Stecker, and G H Baltuch, and J A French, and J A Ferreira, and P M Carney, and D R Labar, and F L Vale
August 2016, Clinical privilege white paper,
W O Tatum, and D B Moore, and M M Stecker, and G H Baltuch, and J A French, and J A Ferreira, and P M Carney, and D R Labar, and F L Vale
May 2020, Practical neurology,
W O Tatum, and D B Moore, and M M Stecker, and G H Baltuch, and J A French, and J A Ferreira, and P M Carney, and D R Labar, and F L Vale
November 2011, Rinsho shinkeigaku = Clinical neurology,
W O Tatum, and D B Moore, and M M Stecker, and G H Baltuch, and J A French, and J A Ferreira, and P M Carney, and D R Labar, and F L Vale
April 2010, Drug and therapeutics bulletin,
W O Tatum, and D B Moore, and M M Stecker, and G H Baltuch, and J A French, and J A Ferreira, and P M Carney, and D R Labar, and F L Vale
August 2000, Clinical privilege white paper,
Copied contents to your clipboard!