-transparent.png){kind=logo}
An in vitro perfused rabbit ovary preparation has been developed to study local factors responsible for the ovulatory process. This preparation enables: (1) isolation of the ovary from systemic influences, (2) direct serial observations of follicle development and ovulation, (3) addition to the perfusing medium of substances that may influence ovulation acting at the level of the ovary, and (4) correlation of the times of individual follicle rupture with ovarian contractile patterns. With this model the temporal requirements for human chorionic gonadotropin in the process of ovulation have been studied. The direct effects on ovulation of prostaglandin F3 alpha (PGF 2 alpha), the antihistamine chlorpheniramine, and calcium deprivation were also investigated. Chlorpheniramine and EDTA each led to inhibition of ovulation and depressed ovarian contractility. The use of the isolated in vitro ovary preparation permits characterization of the local requirements for ovulation.
E E Wallach, and
K H Wright, and
Y Hamada
April 1994,
Endocrinology,
E E Wallach, and
K H Wright, and
Y Hamada
October 1988,
American journal of obstetrics and gynecology,
E E Wallach, and
K H Wright, and
Y Hamada
September 1985,
Journal of autonomic pharmacology,
E E Wallach, and
K H Wright, and
Y Hamada
November 1986,
Biology of reproduction,
E E Wallach, and
K H Wright, and
Y Hamada
October 1992,
Endocrinology,
E E Wallach, and
K H Wright, and
Y Hamada
April 1990,
Acta physiologica Scandinavica,
E E Wallach, and
K H Wright, and
Y Hamada
May 1988,
Endocrinology,
E E Wallach, and
K H Wright, and
Y Hamada
November 1986,
Biology of reproduction,
E E Wallach, and
K H Wright, and
Y Hamada
January 1984,
Cell and tissue research,
E E Wallach, and
K H Wright, and
Y Hamada
April 1993,
Nihon Sanka Fujinka Gakkai zasshi,
