Biomaterial Database

Effects of electrical hippocampal stimulation on acquisition and performance of unidirectional active avoidance response in cats. 1976

K Gralewicz

The influence of electrical stimulation of the posterior part of the hippocampus on acquisition and performance of the conditioned, unidirectional avoidance response was investigated in 26 cats. No significant differences in the speed of learning between stimulated and control animals were observed. However, electrical hippocampal stimulation with parameters 7/s, 100 microamps, 7/s, 200 microamps and 50/s, 100 microamps (1 ms square pulses of negative polarity) facilitated the performance of the avoidance response. Strong hippocampal stimulation (50/s, 200 microamps) caused inhibitory effects. Application of hippocampal stimulation before experimental sessions increased the performance level in comparison to sessions not preceded by hippocampal stimulation.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D002415	Cats	The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)	Felis catus,Felis domesticus,Domestic Cats,Felis domestica,Felis sylvestris catus,Cat,Cat, Domestic,Cats, Domestic,Domestic Cat
D004558	Electric Stimulation	Use of electric potential or currents to elicit biological responses.	Stimulation, Electric,Electrical Stimulation,Electric Stimulations,Electrical Stimulations,Stimulation, Electrical,Stimulations, Electric,Stimulations, Electrical
D004777	Environment	The external elements and conditions which surround, influence, and affect the life and development of an organism or population.	Environmental Impact,Environmental Impacts,Impact, Environmental,Impacts, Environmental,Environments
D006624	Hippocampus	A curved elevation of GRAY MATTER extending the entire length of the floor of the TEMPORAL HORN of the LATERAL VENTRICLE (see also TEMPORAL LOBE). The hippocampus proper, subiculum, and DENTATE GYRUS constitute the hippocampal formation. Sometimes authors include the ENTORHINAL CORTEX in the hippocampal formation.	Ammon Horn,Cornu Ammonis,Hippocampal Formation,Subiculum,Ammon's Horn,Hippocampus Proper,Ammons Horn,Formation, Hippocampal,Formations, Hippocampal,Hippocampal Formations,Hippocampus Propers,Horn, Ammon,Horn, Ammon's,Proper, Hippocampus,Propers, Hippocampus,Subiculums
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001362	Avoidance Learning	A response to a cue that is instrumental in avoiding a noxious experience.	Aversion Behavior,Aversion Learning,Aversive Behavior,Aversive Learning,Avoidance Behavior,Aversion Behaviors,Aversive Behaviors,Avoidance Behaviors,Behavior, Aversion,Behavior, Aversive,Behavior, Avoidance,Behaviors, Aversion,Behaviors, Aversive,Behaviors, Avoidance,Learning, Aversion,Learning, Aversive,Learning, Avoidance