[Diffusion of oxygen and carbon dioxide in a stationary membrane oxygenator]. 1976

V T Gorun, and Z R Karichev, and G Ia Levitskiĭ

Univariate diffusion of oxygen and carbon dioxide through a selective membrane of a stationary membranous oxygenator (SMO) and moving blood film is considered. Through the use of a precise exponential approximation of the oxyhemoglobin dissociation curve [S (p)=1--ae-bp] a partial oxygen pressure distribution [p (x)] along the SMO membrane and a transcedental equation for estimating the value for partial pressure (pa) of the arterialized blood and the SMO efficiency with reference to oxygen have been obtained. A somewhat less exact logarithmic approximation of the summary blood oxygen concentration [C1=a1+b1ln(p--po)] enables it to arrive at an analytical expression for calculating the SMO efficiency with reference to oxygen in a positively definite form. On the other hand, by using logarithmic approximation of the summary carbon dioxide concentration proceeding from the partial CO2 pressure in the blood a partial CO2 pressure distribution along the membrane, as well as an analytical expression for estimating the SMO efficiency with reference to carbon dioxide could be obtained.

UI MeSH Term Description Entries
D008954 Models, Biological Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment. Biological Model,Biological Models,Model, Biological,Models, Biologic,Biologic Model,Biologic Models,Model, Biologic
D010100 Oxygen An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. Dioxygen,Oxygen-16,Oxygen 16
D010107 Oxygenators, Membrane Devices in which blood and oxygen are separated by a semipermeable membrane, generally of Teflon or polypropylene, across which gas exchange occurs. The membrane may be arranged as a series of parallel plates or as a number of hollow fibers; in the latter arrangement, the blood may flow inside the fibers, which are surrounded by gas, or the blood may flow outside the fibers and the gas inside the fibers. (Dorland, 28th ed) Membrane Oxygenator,Membrane Oxygenators,Oxygenator, Membrane
D010108 Oxyhemoglobins A compound formed by the combination of hemoglobin and oxygen. It is a complex in which the oxygen is bound directly to the iron without causing a change from the ferrous to the ferric state. Oxycobalt Hemoglobin,Oxycobalthemoglobin,Oxyhemoglobin,Hemoglobin, Oxycobalt
D011312 Pressure A type of stress exerted uniformly in all directions. Its measure is the force exerted per unit area. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed) Pressures
D002245 Carbon Dioxide A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. Carbonic Anhydride,Anhydride, Carbonic,Dioxide, Carbon
D004058 Diffusion The tendency of a gas or solute to pass from a point of higher pressure or concentration to a point of lower pressure or concentration and to distribute itself throughout the available space. Diffusion, especially FACILITATED DIFFUSION, is a major mechanism of BIOLOGICAL TRANSPORT. Diffusions
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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