What is new about the treatment of diabetic retinopathy by calcium dobesilae (Doxium). 1976

J F Cuendet, and R Sevin

UI MeSH Term Description Entries
D002123 Calcium Dobesilate A drug used to reduce hemorrhage in diabetic retinopathy. Dobesilate Calcium,2,5-Dihydroxybenzenesulfonate,2,5-Dihydroxybenzenesulfonic Acid,Calcium Dobesilate (1:1),Calcium Dobesilate Monoammonium Salt,Calcium Dobesilate Monopotassium Salt,Dexium,Dobica,Doxium,2,5 Dihydroxybenzenesulfonate,2,5 Dihydroxybenzenesulfonic Acid,Calcium, Dobesilate,Dobesilate, Calcium
D002198 Capillary Fragility The susceptibility of CAPILLARIES, under conditions of increased stress, to leakage. Fragility, Capillary
D002199 Capillary Permeability The property of blood capillary ENDOTHELIUM that allows for the selective exchange of substances between the blood and surrounding tissues and through membranous barriers such as the BLOOD-AIR BARRIER; BLOOD-AQUEOUS BARRIER; BLOOD-BRAIN BARRIER; BLOOD-NERVE BARRIER; BLOOD-RETINAL BARRIER; and BLOOD-TESTIS BARRIER. Small lipid-soluble molecules such as carbon dioxide and oxygen move freely by diffusion. Water and water-soluble molecules cannot pass through the endothelial walls and are dependent on microscopic pores. These pores show narrow areas (TIGHT JUNCTIONS) which may limit large molecule movement. Microvascular Permeability,Permeability, Capillary,Permeability, Microvascular,Vascular Permeability,Capillary Permeabilities,Microvascular Permeabilities,Permeabilities, Capillary,Permeabilities, Microvascular,Permeabilities, Vascular,Permeability, Vascular,Vascular Permeabilities
D003930 Diabetic Retinopathy Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION. Diabetic Retinopathies,Retinopathies, Diabetic,Retinopathy, Diabetic
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001557 Benzenesulfonates Organic salts and esters of benzenesulfonic acid.

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