Biomaterial Database

[Gene instability induced by mobile genetic elements in Drosophila melanogaster]. 1999

H R Shcherbata, and D V Maksymiv, and Ia I Chernyk

The genetic instability of Drosophila melanogaster genes induced by the mobile genetic elements is reviewed. The main attention is paid to genetic instability depended on types of crossing. Data on the possibility of genetic instability induction by the chemical and physical (X-rays, heat-shock) agents and their complex effect are cited. It was shown that a number of agents which cause mutagenic effect realize their action by involving of mobile genetic elements.

UI	MeSH Term	Description	Entries
D003434	Crossing Over, Genetic	The reciprocal exchange of segments at corresponding positions along pairs of homologous CHROMOSOMES by symmetrical breakage and crosswise rejoining forming cross-over sites (HOLLIDAY JUNCTIONS) that are resolved during CHROMOSOME SEGREGATION. Crossing-over typically occurs during MEIOSIS but it may also occur in the absence of meiosis, for example, with bacterial chromosomes, organelle chromosomes, or somatic cell nuclear chromosomes.	Crossing Over,Crossing-Over, Genetic,Crossing Overs,Genetic Crossing Over,Genetic Crossing-Over
D004331	Drosophila melanogaster	A species of fruit fly frequently used in genetics because of the large size of its chromosomes.	D. melanogaster,Drosophila melanogasters,melanogaster, Drosophila
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D014644	Genetic Variation	Genotypic differences observed among individuals in a population.	Genetic Diversity,Variation, Genetic,Diversity, Genetic,Diversities, Genetic,Genetic Diversities,Genetic Variations,Variations, Genetic
D017344	Genes, Insect	The functional hereditary units of INSECTS.	Insect Genes,Gene, Insect,Insect Gene
D020071	Interspersed Repetitive Sequences	Copies of transposable elements interspersed throughout the genome, some of which are still active and often referred to as "jumping genes". There are two classes of interspersed repetitive elements. Class I elements (or RETROELEMENTS - such as retrotransposons, retroviruses, LONG INTERSPERSED NUCLEOTIDE ELEMENTS and SHORT INTERSPERSED NUCLEOTIDE ELEMENTS) transpose via reverse transcription of an RNA intermediate. Class II elements (or DNA TRANSPOSABLE ELEMENTS - such as transposons, Tn elements, insertion sequence elements and mobile gene cassettes of bacterial integrons) transpose directly from one site in the DNA to another.	Dispersed Repetitive Sequences,Genes, Jumping,Interspersed Repetitive Elements,Jumping Genes,Mobile Genetic Elements,Repetitive Sequences, Dispersed,Repetitive Sequences, Interspersed,Elements, Mobile Genetic,Genetic Elements, Mobile,Dispersed Repetitive Sequence,Element, Interspersed Repetitive,Element, Mobile Genetic,Elements, Interspersed Repetitive,Gene, Jumping,Genetic Element, Mobile,Interspersed Repetitive Element,Interspersed Repetitive Sequence,Jumping Gene,Mobile Genetic Element,Repetitive Element, Interspersed,Repetitive Elements, Interspersed,Repetitive Sequence, Dispersed,Repetitive Sequence, Interspersed,Sequence, Dispersed Repetitive,Sequence, Interspersed Repetitive,Sequences, Dispersed Repetitive,Sequences, Interspersed Repetitive