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The existence of substances in corn germ, which induce a positive response in pigeon crop test, has been previously reported by Okamoto and Takahashi in 1974. Following this first experiment, one of these substances was identified as ferulic acid by purification. In the present experiment FSH, LH and prolactin levels in the serum and the pituitary tissue of castrated male rats and EP (estradiol benzoate and progesterone) treated male rats were determined by radioimmunoassay at 5 to 180 min. after intravenous injection with 1 mg of ferulic acid. It was noted that FSH release only was promoted significantly at 5 min. after the injection, whereas LH and prolactin releases were inhibited at 5 to 10 min. after the injection. A rebound effect was noted in LH and prolactin releases after the injection.
R Okamoto, and
S Sakamoto, and
K Noguchi
February 1976,
Endocrinology,
R Okamoto, and
S Sakamoto, and
K Noguchi
October 1972,
Acta obstetrica et gynaecologica Japonica,
R Okamoto, and
S Sakamoto, and
K Noguchi
June 1974,
Endocrinologia japonica,
R Okamoto, and
S Sakamoto, and
K Noguchi
October 1977,
No shinkei geka. Neurological surgery,
R Okamoto, and
S Sakamoto, and
K Noguchi
February 1971,
Endocrinology,
R Okamoto, and
S Sakamoto, and
K Noguchi
January 1986,
The Prostate,
R Okamoto, and
S Sakamoto, and
K Noguchi
May 1974,
Wiener klinische Wochenschrift,
R Okamoto, and
S Sakamoto, and
K Noguchi
May 1978,
Endokrinologie,
R Okamoto, and
S Sakamoto, and
K Noguchi
September 1996,
Revista espanola de fisiologia,
R Okamoto, and
S Sakamoto, and
K Noguchi
October 1977,
Brain research,
