Survival analysis of Thai patients with non-small-cell lung cancer undergoing surgical resection. 1999

P Riantawan, and T Koanantakool, and T Chotivatanapong, and M Wongsangiem
Division of Medicine, Central Chest Hospital, Nonthaburi, Thailand.

This study examined the survival duration among patients with non-small-cell lung cancer (NSCLC) undergoing surgical resection from January 1988 to December 1992 at the Central Chest Hospital, Thailand. Patients were followed-up until death or survival as of September 1997. Survival durations for different stages were analysed by Kaplan-Meier analysis and log rank test. A total of 127 patients with histologically proved NSCLC underwent 79 lobectomies, 9 bilobectomies, 39 pneumonectomies during 1988-1992. The mean age was 60 years (SD 10.4). There were 103 males and 24 females. Percentage of histologic types were: 59 per cent adenoCA, 35 per cent squamous cell CA, and 6 per cent large cellCA. Survival analysis was feasible in 88 patients, 38 alive and 50 deaths. 1-yr, 2-yr, and 5-yr survival were as following: 85 per cent, 78 per cent, and 60 per cent in stage 1 (n = 47); 70 per cent, 50 per cent, and 30 per cent in stage 2 (n = 12); and 54 per cent, 23 per cent, and 15 per cent in stage 3a (n = 29) [log rank 19.06, df 2, p = 0.0001]. Based on the present study, the survival outcome in patients with lung cancer beyond stage 1 is uniformly poor. Measures should be made to diagnose early stage disease and expedite surgery in order that a better survival outcome can be achieved.

UI MeSH Term Description Entries
D008175 Lung Neoplasms Tumors or cancer of the LUNG. Cancer of Lung,Lung Cancer,Pulmonary Cancer,Pulmonary Neoplasms,Cancer of the Lung,Neoplasms, Lung,Neoplasms, Pulmonary,Cancer, Lung,Cancer, Pulmonary,Cancers, Lung,Cancers, Pulmonary,Lung Cancers,Lung Neoplasm,Neoplasm, Lung,Neoplasm, Pulmonary,Pulmonary Cancers,Pulmonary Neoplasm
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D002289 Carcinoma, Non-Small-Cell Lung A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy. Carcinoma, Non-Small Cell Lung,Non-Small Cell Lung Cancer,Non-Small Cell Lung Carcinoma,Non-Small-Cell Lung Carcinoma,Nonsmall Cell Lung Cancer,Carcinoma, Non Small Cell Lung,Carcinomas, Non-Small-Cell Lung,Lung Carcinoma, Non-Small-Cell,Lung Carcinomas, Non-Small-Cell,Non Small Cell Lung Carcinoma,Non-Small-Cell Lung Carcinomas
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D000369 Aged, 80 and over Persons 80 years of age and older. Oldest Old
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective

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