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Cardiac output (isotopic dilution method) and systolic time intervals were studied in 11 sustained and 8 borderline essential hypertensive patients, before and after intravenous administration of atenolol, a potent beta-blocking agent. Atenolol decreased significantly (p less than 0.01) cardiac output and heart rate. In borderline hypertensives, the preejection periods were significantly reduced. Atenolol prolonged the preejection periods more significantly (p less than 0.01) in borderline than in permanent hypertensives. Non invasive hemodynamic technics enabled the cardiac performance to be evaluated in hypertensives and the contribution of neurogenic factors in borderline hypertension to be estimated.
J P Lehner, and
A Simon, and
A Kehder, and
Y Weiss, and
C Tzincoca, and
M Safar
December 1979,
Clinical science (London, England : 1979),
J P Lehner, and
A Simon, and
A Kehder, and
Y Weiss, and
C Tzincoca, and
M Safar
August 1976,
Lakartidningen,
J P Lehner, and
A Simon, and
A Kehder, and
Y Weiss, and
C Tzincoca, and
M Safar
January 1976,
Acta medica Scandinavica,
J P Lehner, and
A Simon, and
A Kehder, and
Y Weiss, and
C Tzincoca, and
M Safar
January 1978,
British heart journal,
J P Lehner, and
A Simon, and
A Kehder, and
Y Weiss, and
C Tzincoca, and
M Safar
November 1980,
British journal of clinical pharmacology,
J P Lehner, and
A Simon, and
A Kehder, and
Y Weiss, and
C Tzincoca, and
M Safar
January 1967,
Munchener medizinische Wochenschrift (1950),
J P Lehner, and
A Simon, and
A Kehder, and
Y Weiss, and
C Tzincoca, and
M Safar
June 1981,
Zhonghua xin xue guan bing za zhi,
J P Lehner, and
A Simon, and
A Kehder, and
Y Weiss, and
C Tzincoca, and
M Safar
June 1972,
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J P Lehner, and
A Simon, and
A Kehder, and
Y Weiss, and
C Tzincoca, and
M Safar
October 1987,
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J P Lehner, and
A Simon, and
A Kehder, and
Y Weiss, and
C Tzincoca, and
M Safar
January 1993,
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