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2,4-dichlorophenoxyacetic acid and its derivatives (collectively known as 2,4-D) are herbicides used to control a wide variety of broadleaf and woody plants. The genetic toxicity of an ester (2,4-D 2-butoxyethylester) and two salts (2,4-D isopropylamine and 2,4-D triisopropanolamine) was investigated in cultured mammalian cells. The end points used were the induction of chromosomal aberrations in primary cultures of rat lymphocytes and forward mutations at the HGPRT locus of Chinese hamster ovary cells. There was no evidence of genotoxicity for the test materials in the experimental systems used. These results were consistent with the general lack of genotoxic potential for 2,4-D in a number of other test systems.
B B Gollapudi, and
J M Charles, and
V A Linscombe, and
S J Day, and
J S Bus
March 1968,
Journal of medicinal chemistry,
B B Gollapudi, and
J M Charles, and
V A Linscombe, and
S J Day, and
J S Bus
January 1977,
Journal of agricultural and food chemistry,
B B Gollapudi, and
J M Charles, and
V A Linscombe, and
S J Day, and
J S Bus
December 2009,
Analytical chemistry,
B B Gollapudi, and
J M Charles, and
V A Linscombe, and
S J Day, and
J S Bus
November 1949,
Science (New York, N.Y.),
B B Gollapudi, and
J M Charles, and
V A Linscombe, and
S J Day, and
J S Bus
September 1956,
Plant physiology,
B B Gollapudi, and
J M Charles, and
V A Linscombe, and
S J Day, and
J S Bus
January 2000,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
B B Gollapudi, and
J M Charles, and
V A Linscombe, and
S J Day, and
J S Bus
January 2020,
The Journal of toxicological sciences,
B B Gollapudi, and
J M Charles, and
V A Linscombe, and
S J Day, and
J S Bus
June 2020,
Toxicology in vitro : an international journal published in association with BIBRA,
B B Gollapudi, and
J M Charles, and
V A Linscombe, and
S J Day, and
J S Bus
March 2005,
Toxicology in vitro : an international journal published in association with BIBRA,
B B Gollapudi, and
J M Charles, and
V A Linscombe, and
S J Day, and
J S Bus
June 1995,
Environmental science & technology,
