Dermatitis in the rubber industry has diminished markedly in this century, but the problem still is the second most common occupational disease. Contributing agents include natural rubber, as latex concentrate or dry crumb, as well as the various additives used for conditioning. Primary, secondary, and tertiary prevention all have roles in reduction of incidence and severity of impairment. The choice of gloves and skin care methods must be based on a consideration of the efficacy of the materials and the environment in which they will be used. Careful attention to diagnosis yields benefits in treatment course and impairment reduction. Teamwork by occupational physicians, nurses, industrial hygienists, employees, and management is required.