Biomaterial Database

Controls in patterning and diversification of somatic muscles during Drosophila embryogenesis. 1999

M Frasch

Department of Biochemistry and Molecular Biology Mount Sinai School of Medicine Box 1020, New York, New York 10029, USA.

Recent genetic studies in Drosophila have provided important insights into the pathways determining the formation and diversification of body wall muscles. These pathways control a progressive subdivision of the mesoderm, ultimately leading to the specification of individual cells, the muscle founders, which are endowed with genetic programs capable of generating distinct muscle fibers. A network of activities of transcriptional regulators, signaling pathways, and lineage genes is beginning to emerge which controls successive steps of this muscle patterning and differentiation process.

UI	MeSH Term	Description	Entries
D008648	Mesoderm	The middle germ layer of an embryo derived from three paired mesenchymal aggregates along the neural tube.	Mesenchyme,Dorsal Mesoderm,Intermediate Mesoderm,Lateral Plate Mesoderm,Mesenchyma,Paraxial Mesoderm,Dorsal Mesoderms,Intermediate Mesoderms,Lateral Plate Mesoderms,Mesenchymas,Mesoderm, Dorsal,Mesoderm, Intermediate,Mesoderm, Lateral Plate,Mesoderm, Paraxial,Mesoderms, Dorsal,Mesoderms, Intermediate,Mesoderms, Lateral Plate,Mesoderms, Paraxial,Paraxial Mesoderms,Plate Mesoderm, Lateral,Plate Mesoderms, Lateral
D009132	Muscles	Contractile tissue that produces movement in animals.	Muscle Tissue,Muscle,Muscle Tissues,Tissue, Muscle,Tissues, Muscle
D002455	Cell Division	The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.	M Phase,Cell Division Phase,Cell Divisions,Division Phase, Cell,Division, Cell,Divisions, Cell,M Phases,Phase, Cell Division,Phase, M,Phases, M
D004330	Drosophila	A genus of small, two-winged flies containing approximately 900 described species. These organisms are the most extensively studied of all genera from the standpoint of genetics and cytology.	Fruit Fly, Drosophila,Drosophila Fruit Flies,Drosophila Fruit Fly,Drosophilas,Flies, Drosophila Fruit,Fly, Drosophila Fruit,Fruit Flies, Drosophila
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D019521	Body Patterning	The processes occurring in early development that direct morphogenesis. They specify the body plan ensuring that cells will proceed to differentiate, grow, and diversify in size and shape at the correct relative positions. Included are axial patterning, segmentation, compartment specification, limb position, organ boundary patterning, blood vessel patterning, etc.	Axial Patterning (Embryology),Embryonic Pattern Formation,Polarity of Development,Body Pattern Formation,Body Pattern Specification,Embryonic Pattern Specification,Development Polarity,Embryonic Pattern Formations,Formation, Embryonic Pattern,Pattern Formation, Body,Pattern Formation, Embryonic,Pattern Specification, Body,Pattern Specification, Embryonic,Patterning, Axial (Embryology),Patterning, Body,Specification, Body Pattern,Specification, Embryonic Pattern