Biomaterial Database

Dental anesthetic management of epidermolysis bullosa: a new approach. 1975

W C Morgan

Epidermolysis bullosa is a rare blister-producing skin disorder that has been of some concern to dentists in the past. Dental treatment has been attempted on an outpatient basis with local anesthesia. In some of these patients, local anesthesia has caused large intraoral bullae. Other methods of treatment have been sought, including the use of general anesthesia and intramuscular sedation. This is a report of a case in which intravenous ketamine hydrochloride was used with good results. We believe this method has much to offer in the treatment of these patients.

UI	MeSH Term	Description	Entries
D007649	Ketamine	A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.	2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone,CI-581,Calipsol,Calypsol,Kalipsol,Ketalar,Ketamine Hydrochloride,Ketanest,Ketaset,CI 581,CI581
D008297	Male		Males
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D003793	Dental Restoration, Permanent	A restoration designed to remain in service for not less than 20 to 30 years, usually made of gold casting, cohesive gold, or amalgam. (Jablonski, Dictionary of Dentistry, 1992)	Dental Fillings, Permanent,Dental Filling, Permanent,Dental Permanent Filling,Dental Permanent Fillings,Dental Restorations, Permanent,Filling, Dental Permanent,Filling, Permanent Dental,Fillings, Dental Permanent,Fillings, Permanent Dental,Permanent Dental Filling,Permanent Dental Fillings,Permanent Dental Restoration,Permanent Dental Restorations,Permanent Filling, Dental,Permanent Fillings, Dental,Restoration, Permanent Dental,Restorations, Permanent Dental
D004820	Epidermolysis Bullosa	Group of genetically determined disorders characterized by the blistering of skin and mucosae. There are four major forms: acquired, simple, junctional, and dystrophic. Each of the latter three has several varieties.	Acantholysis Bullosa
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000766	Anesthesia, Dental	A range of methods used to reduce pain and anxiety during dental procedures.	Dental Anesthesia
D000771	Anesthesia, Intravenous	Process of administering an anesthetic through injection directly into the bloodstream.	Anesthesias, Intravenous,Intravenous Anesthesia,Intravenous Anesthesias
D014081	Tooth Extraction	The surgical removal of a tooth. (Dorland, 28th ed)	Extraction, Tooth,Extractions, Tooth,Tooth Extractions