-transparent.png){kind=logo}
In the UK, there have been few studies of the seroprevalence of antibodies to hepatitis C virus (anti-HCV). As part of an ongoing prevalence study of HCV in injecting drug users, we have developed a technique for detecting anti-HCV in blood spots dried on filter paper using a commercially available assay. Subjects with and without serum anti-HCV were studied. The manufacturer's recommended cut-off (CO) for a positive anti-HCV result is kit-dependent, and therefore a ratio of test result (T) to kit CO was used to standardize results. T/CO values greater than 0.99 had a sensitivity of 100% and a specificity of 87.5% for anti-HCV detection. T/CO values greater than 1.99 had a sensitivity of 97.2% and a specificity of 100%. Hence, testing dried blood spots may be useful for detecting anti-HCV in epidemiological studies and as a diagnostic test in patients with poor peripheral venous access.
B McCarron, and
R Fox, and
K Wilson, and
S Cameron, and
J McMenamin, and
G McGregor, and
A Pithie, and
D Goldberg
June 2012,
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology,
B McCarron, and
R Fox, and
K Wilson, and
S Cameron, and
J McMenamin, and
G McGregor, and
A Pithie, and
D Goldberg
April 2014,
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology,
B McCarron, and
R Fox, and
K Wilson, and
S Cameron, and
J McMenamin, and
G McGregor, and
A Pithie, and
D Goldberg
June 2013,
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology,
B McCarron, and
R Fox, and
K Wilson, and
S Cameron, and
J McMenamin, and
G McGregor, and
A Pithie, and
D Goldberg
September 2019,
Viruses,
B McCarron, and
R Fox, and
K Wilson, and
S Cameron, and
J McMenamin, and
G McGregor, and
A Pithie, and
D Goldberg
October 2010,
Scandinavian journal of clinical and laboratory investigation,
B McCarron, and
R Fox, and
K Wilson, and
S Cameron, and
J McMenamin, and
G McGregor, and
A Pithie, and
D Goldberg
December 2017,
Public health,
B McCarron, and
R Fox, and
K Wilson, and
S Cameron, and
J McMenamin, and
G McGregor, and
A Pithie, and
D Goldberg
May 2006,
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology,
B McCarron, and
R Fox, and
K Wilson, and
S Cameron, and
J McMenamin, and
G McGregor, and
A Pithie, and
D Goldberg
November 1997,
Journal of virological methods,
B McCarron, and
R Fox, and
K Wilson, and
S Cameron, and
J McMenamin, and
G McGregor, and
A Pithie, and
D Goldberg
April 2021,
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology,
B McCarron, and
R Fox, and
K Wilson, and
S Cameron, and
J McMenamin, and
G McGregor, and
A Pithie, and
D Goldberg
September 2007,
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology,
