Epidemiological limitations of the nitrogen closing volume test. 1976

F V Rasmussen, and P C Solvsteen, and L H Andersen

Closing volume was measured in 216 men aged 46-68 years. They were divided in 5 age groups and classified as either symptomatic or asymptomatic according to answer to standardized interviews. In 3 of 5 age groups mean value for closing volume percent (CV%) for symptomatic persons was lower than the mean value for asymptomatic persons. CV% is not considered useful as the dependent variable in a multiple regression analysis. In all 5 age groups the mean value of slope of alveolar plateau was higher for symptomatic than for asymptomatic persons. Slope af alveolar plateau is considered useful as dependent variable in a multiple regression analysis. One of the reasons for the false negative CV%-values is believed to be influence of increased uneven and sequential ventilation of the lungs, expressed in the slope of alveolar plateau.

UI MeSH Term Description Entries
D008173 Lung Diseases, Obstructive Any disorder marked by obstruction of conducting airways of the lung. AIRWAY OBSTRUCTION may be acute, chronic, intermittent, or persistent. Obstructive Lung Diseases,Obstructive Pulmonary Diseases,Lung Disease, Obstructive,Obstructive Lung Disease,Obstructive Pulmonary Disease,Pulmonary Disease, Obstructive,Pulmonary Diseases, Obstructive
D008176 Lung Volume Measurements Measurement of the amount of air that the lungs may contain at various points in the respiratory cycle. Lung Capacities,Lung Volumes,Capacity, Lung,Lung Capacity,Lung Volume,Lung Volume Measurement,Measurement, Lung Volume,Volume, Lung
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009584 Nitrogen An element with the atomic symbol N, atomic number 7, and atomic weight [14.00643; 14.00728]. Nitrogen exists as a diatomic gas and makes up about 78% of the earth's atmosphere by volume. It is a constituent of proteins and nucleic acids and found in all living cells.
D012044 Regression Analysis Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable. Regression Diagnostics,Statistical Regression,Analysis, Regression,Analyses, Regression,Diagnostics, Regression,Regression Analyses,Regression, Statistical,Regressions, Statistical,Statistical Regressions
D005105 Expiratory Reserve Volume The extra volume of air that can be expired with maximum effort beyond the level reached at the end of a normal, quiet expiration. Common abbreviation is ERV. Expiratory Reserve Volumes,Reserve Volume, Expiratory,Reserve Volumes, Expiratory,Volume, Expiratory Reserve,Volumes, Expiratory Reserve
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D014797 Vital Capacity The volume of air that is exhaled by a maximal expiration following a maximal inspiration. Forced Vital Capacity,Capacities, Forced Vital,Capacities, Vital,Capacity, Forced Vital,Capacity, Vital,Forced Vital Capacities,Vital Capacities,Vital Capacities, Forced,Vital Capacity, Forced

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