Biomaterial Database

[The Sjögren-Gougerot syndrome]. 1976

M Perrier

The Sjögren-Gougerot syndrome represents a rare disease of the collagenous tissue characterized by the three symptoms Xerophtalmy, Xerostomy, polyarthritis. Women after the menopause are the most affected. Oral symptoms addup to diverse dermatological manifestations. The bilateral parotidic swelling and systemic complications accompany the disease, and the immunological disorder is coupled with hypergammaglobulinemia. Prognosis is very reserved and treatment delicate.

UI	MeSH Term	Description	Entries
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D001809	Blood Viscosity	The internal resistance of the BLOOD to shear forces. The in vitro measure of whole blood viscosity is of limited clinical utility because it bears little relationship to the actual viscosity within the circulation, but an increase in the viscosity of circulating blood can contribute to morbidity in patients suffering from disorders such as SICKLE CELL ANEMIA and POLYCYTHEMIA.	Blood Viscosities,Viscosities, Blood,Viscosity, Blood
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006942	Hypergammaglobulinemia	An excess of GAMMA-GLOBULINS in the serum due to chronic infections or PARAPROTEINEMIAS.	Hyperimmunoglobulinemia,Hypergammaglobulinemias,Hyperimmunoglobulinemias
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly
D001168	Arthritis	Acute or chronic inflammation of JOINTS.	Oligoarthritis,Polyarthritis,Arthritides,Oligoarthritides,Polyarthritides
D012859	Sjogren's Syndrome	Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.	Sicca Syndrome,Sjogren Syndrome,Sjogrens Syndrome,Syndrome, Sicca,Syndrome, Sjogren's
D014985	Xerophthalmia	Dryness of the eye surfaces caused by deficiency of tears or conjunctival secretions. It may be associated with vitamin A deficiency, trauma, or any condition in which the eyelids do not close completely.	Xerophthalmias
D014987	Xerostomia	Decreased salivary flow.	Asialia,Hyposalivation,Mouth Dryness,Asialias,Dryness, Mouth,Hyposalivations,Xerostomias