System for measuring isolated rat soleus muscle belly response to tetanic stimulation. 2000

A Koren, and R Blenkus
Institute of Physiology, Medical Faculty, University of Ljubljana, Slovenia.

A novel system for simultaneous measurements of isotonic muscle contraction and transversal muscle belly displacement in the isolated rat soleus muscle was designed. The system simultaneously records tetanic contraction of the muscle and transversal displacements of the muscle belly. The tetanic rise times (TRT) and muscle belly displacement times (BDRT) were measured at different proton loads induced by CO2 at 1%, 5% and 30%. The measurements of muscle belly displacement enabled us to follow the water shift into the muscle tissue during the tetanic activity. Acidosis provoked by 30% CO2 irreversibly increased the BDRT, however the TRT were not changed.

UI MeSH Term Description Entries
D007551 Isotonic Contraction Muscle contraction with negligible change in the force of contraction but shortening of the distance between the origin and insertion. Contraction, Isotonic,Contractions, Isotonic,Isotonic Contractions
D010827 Physiology The biological science concerned with the life-supporting properties, functions, and processes of living organisms or their parts.
D011522 Protons Stable elementary particles having the smallest known positive charge, found in the nuclei of all elements. The proton mass is less than that of a neutron. A proton is the nucleus of the light hydrogen atom, i.e., the hydrogen ion. Hydrogen Ions,Hydrogen Ion,Ion, Hydrogen,Ions, Hydrogen,Proton
D011930 Reaction Time The time from the onset of a stimulus until a response is observed. Response Latency,Response Speed,Response Time,Latency, Response,Reaction Times,Response Latencies,Response Times,Speed, Response,Speeds, Response
D012016 Reference Values The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality. Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D002245 Carbon Dioxide A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. Carbonic Anhydride,Anhydride, Carbonic,Dioxide, Carbon
D004558 Electric Stimulation Use of electric potential or currents to elicit biological responses. Stimulation, Electric,Electrical Stimulation,Electric Stimulations,Electrical Stimulations,Stimulation, Electrical,Stimulations, Electric,Stimulations, Electrical
D000138 Acidosis A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up. Metabolic Acidosis,Acidoses,Acidoses, Metabolic,Acidosis, Metabolic,Metabolic Acidoses
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D017208 Rats, Wistar A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain. Wistar Rat,Rat, Wistar,Wistar Rats

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