Biomaterial Database

The progression of gingivitis to periodontitis in the beagle dog: a histological and morphometric investigation. 1976

J V Soames, and D N Entwisle, and R M Davies

The spread of the inflammatory cell infiltrate in the progression of gingivitis to periodontitis in the Beagle dog follows the course of blood vessels. Buccolingually this is towards the periosteal surface of the bone and interdentally towards the midpoint and angles of the interdental septum. Interdentally the path of spread may be modified by the local anatomy. Bone resoprtion buccolingually progresses from the periosteal surface towards the tooth and interproximally along the crest of the interdental septa and within marrow spaces. The pathway of spread of the inflammatory cell infiltrate, the anatomic relationships of the teeth to each other and the original morphology of the alveolar bone may influence the pattern of bone loss in periodontitis.

UI	MeSH Term	Description	Entries
D010518	Periodontitis	Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)	Pericementitis,Pericementitides,Periodontitides
D010519	Periodontium	The structures surrounding and supporting the tooth. Periodontium includes the gum (GINGIVA), the alveolar bone (ALVEOLAR PROCESS), the DENTAL CEMENTUM, and the PERIODONTAL LIGAMENT.	Paradentium,Parodontium,Tooth Supporting Structures,Paradentiums,Parodontiums,Periodontiums,Structure, Tooth Supporting,Structures, Tooth Supporting,Supporting Structure, Tooth,Supporting Structures, Tooth,Tooth Supporting Structure
D010521	Periosteum	Thin outer membrane that surrounds a bone. It contains CONNECTIVE TISSUE, CAPILLARIES, nerves, and a number of cell types.
D001808	Blood Vessels	Any of the tubular vessels conveying the blood (arteries, arterioles, capillaries, venules, and veins).	Blood Vessel,Vessel, Blood,Vessels, Blood
D003238	Connective Tissue	Tissue that supports and binds other tissues. It consists of CONNECTIVE TISSUE CELLS embedded in a large amount of EXTRACELLULAR MATRIX.	Connective Tissues,Tissue, Connective,Tissues, Connective
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D005881	Gingiva	Oral tissue surrounding and attached to TEETH.	Gums,Interdental Papilla,Papilla, Interdental,Gum
D005891	Gingivitis	Inflammation of gum tissue (GINGIVA) without loss of connective tissue.	Gingivitides
D000539	Alveolar Process	The thickest and spongiest part of the maxilla and mandible hollowed out into deep cavities for the teeth.	Alveolar Ridge,Alveolar Processes,Process, Alveolar,Processes, Alveolar,Ridge, Alveolar
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia