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Photon irradiation of the abdomen may be accompanied by complications due to a decrease in the immune defense of the recipient. Since peritoneal macrophages are an important component of the immune system, we examined the phagocytic activity and oxygen superoxide anion generation by peritoneal macrophages from rats 2 and 4 weeks after abdominal irradiation with 6 MV photons applying a single dose of 2 Gy. Two and 4 weeks after irradiation, peritoneal macrophages were harvested and their capacity to engulf latex particles and to produce oxygen superoxide anions was determined. Non-irradiated rats, treated identically otherwise, served as controls. Two weeks after irradiation the phagocytic capacity and oxygen superoxide anion generation decreased by 61 and 70%, respectively, compared with controls. This tendency persisted after 4 weeks post irradiation, the decrease in both functions being 50 and 74%, respectively. It is suggested that the altered function of peritoneal macrophages following irradiation may further compromise the immune defense in patients receiving abdominal radiotherapy.
H Salman, and
M Bergman, and
H Bessler, and
E Fenig, and
J Weiss, and
B Beilin, and
M Djaldetti
May 1987,
Meditsinskaia radiologiia,
H Salman, and
M Bergman, and
H Bessler, and
E Fenig, and
J Weiss, and
B Beilin, and
M Djaldetti
April 1973,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
H Salman, and
M Bergman, and
H Bessler, and
E Fenig, and
J Weiss, and
B Beilin, and
M Djaldetti
September 1979,
Acta endocrinologica,
H Salman, and
M Bergman, and
H Bessler, and
E Fenig, and
J Weiss, and
B Beilin, and
M Djaldetti
January 1984,
Bratislavske lekarske listy,
H Salman, and
M Bergman, and
H Bessler, and
E Fenig, and
J Weiss, and
B Beilin, and
M Djaldetti
January 2006,
Journal of biochemical and molecular toxicology,
H Salman, and
M Bergman, and
H Bessler, and
E Fenig, and
J Weiss, and
B Beilin, and
M Djaldetti
November 2003,
ANZ journal of surgery,
H Salman, and
M Bergman, and
H Bessler, and
E Fenig, and
J Weiss, and
B Beilin, and
M Djaldetti
December 1983,
International journal of radiation biology and related studies in physics, chemistry, and medicine,
H Salman, and
M Bergman, and
H Bessler, and
E Fenig, and
J Weiss, and
B Beilin, and
M Djaldetti
January 1973,
Journal of the Reticuloendothelial Society,
H Salman, and
M Bergman, and
H Bessler, and
E Fenig, and
J Weiss, and
B Beilin, and
M Djaldetti
January 2010,
Clinics (Sao Paulo, Brazil),
H Salman, and
M Bergman, and
H Bessler, and
E Fenig, and
J Weiss, and
B Beilin, and
M Djaldetti
January 1985,
Mycopathologia,
