Biomaterial Database

Cytotoxicity of temporary crown and bridge materials. 1976

B L Dahl, and J Orstavik

In vitro cytotoxicity of freshly prepared temporary crown and bridge materials was studied using mouse fibroblasts prelabelled with 3H-thymidine grown in shake flask cultures. Cytotoxicity was measured as (1) lack of cell multiplication, (2) stainability with Trypan blue and (3) release of 3H-labelled material to the culture medium. All the materials tested (zinc oxide-eugenol cement (ZOE), Scutan and Sevriton) were cytotoxic in this system, ZOE most strongly. This finding favours the view that the in vitro cytotoxicity of dental materials should not be used alone as a screening test for their biological compatibility under clinical conditions since clinical experience and previous in vivo findings have established that ZOE is biologically well tolerated by the dental tissues.

UI	MeSH Term	Description	Entries
D002455	Cell Division	The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.	M Phase,Cell Division Phase,Cell Divisions,Division Phase, Cell,Division, Cell,Divisions, Cell,M Phases,Phase, Cell Division,Phase, M,Phases, M
D002470	Cell Survival	The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.	Cell Viability,Cell Viabilities,Survival, Cell,Viabilities, Cell,Viability, Cell
D003442	Crowns	A prosthetic restoration that reproduces the entire surface anatomy of the visible natural crown of a tooth. It may be partial (covering three or more surfaces of a tooth) or complete (covering all surfaces). It is made of gold or other metal, porcelain, or resin.	Dental Crowns,Crown, Dental,Crowns, Dental,Dental Crown,Crown
D003764	Dental Materials	Materials used in the production of dental bases, restorations, impressions, prostheses, etc.	Dental Material,Material, Dental,Materials, Dental
D003794	Dental Restoration, Temporary	A prosthesis or restoration placed for a limited period, from several days to several months, which is designed to seal the tooth and maintain its position until a permanent restoration (DENTAL RESTORATION, PERMANENT) will replace it. (From Jablonski, Dictionary of Dentistry, 1992)	Dental Fillings, Temporary,Dental Prosthesis, Temporary,Dental Filling, Temporary,Dental Restorations, Temporary,Filling, Temporary Dental,Fillings, Temporary Dental,Restoration, Temporary Dental,Restorations, Temporary Dental,Temporary Dental Filling,Temporary Dental Fillings,Temporary Dental Restoration,Temporary Dental Restorations,Dental Prostheses, Temporary,Prosthesis, Temporary Dental,Temporary Dental Prostheses,Temporary Dental Prosthesis
D003833	Denture, Partial, Temporary	A partial denture intended for short-term use in a temporary or emergency situation.	Dental Prosthesis, Interim,Interim Dental Prosthesis,Interim Prosthesis Dental,Dental Prostheses, Interim,Dental, Interim Prosthesis,Dentals, Interim Prosthesis,Interim Dental Prostheses,Interim Prosthesis Dentals,Prostheses, Interim Dental,Prosthesis Dental, Interim,Prosthesis Dentals, Interim,Prosthesis, Interim Dental
D005347	Fibroblasts	Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.	Fibroblast
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D051379	Mice	The common name for the genus Mus.	Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus