A Krüppel-like zinc finger protein is involved in nitrogen-fixing root nodule organogenesis. 2000

F Frugier, and S Poirier, and B Satiat-Jeunemaître, and A Kondorosi, and M Crespi
Institut des Sciences Végétales, Centre National de la Recherche Scientifique (CNRS), F-91198 Gif-sur-Yvette Cedex, France.

Mechanisms regulating plant host differentiation of the nitrogen-fixing root nodules remain mostly unknown. Sinorhizobium meliloti induces this process in Medicago sativa in which the Mszpt2-1 gene is expressed in vascular bundles of roots and nodules. This gene codes for a Krüppel-like zinc finger protein, a class of transcription factors involved in many animal developmental processes. Expression of Mszpt2-1 in yeast cells conferred osmotic tolerance. Antisense plants grew normally but developed nonfunctional nodules, in which differentiation of the nitrogen-fixing zone and bacterial invasion were arrested. Hence, a vascular bundle-associated Krüppel-like gene is required for the formation of the central nitrogen-fixing zone of the root nodule.

UI MeSH Term Description Entries
D008969 Molecular Sequence Data Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories. Sequence Data, Molecular,Molecular Sequencing Data,Data, Molecular Sequence,Data, Molecular Sequencing,Sequencing Data, Molecular
D009586 Nitrogen Fixation The process in certain BACTERIA; FUNGI; and CYANOBACTERIA converting free atmospheric NITROGEN to biologically usable forms of nitrogen, such as AMMONIA; NITRATES; and amino compounds. Diazotrophy,Diazotrophic Activity,Dinitrogen Fixation,N2 Fixation,Activities, Diazotrophic,Activity, Diazotrophic,Diazotrophic Activities,Fixation, Dinitrogen,Fixation, N2,Fixation, Nitrogen
D010940 Plant Proteins Proteins found in plants (flowers, herbs, shrubs, trees, etc.). The concept does not include proteins found in vegetables for which PLANT PROTEINS, DIETARY is available. Plant Protein,Protein, Plant,Proteins, Plant
D011993 Recombinant Fusion Proteins Recombinant proteins produced by the GENETIC TRANSLATION of fused genes formed by the combination of NUCLEIC ACID REGULATORY SEQUENCES of one or more genes with the protein coding sequences of one or more genes. Fusion Proteins, Recombinant,Recombinant Chimeric Protein,Recombinant Fusion Protein,Recombinant Hybrid Protein,Chimeric Proteins, Recombinant,Hybrid Proteins, Recombinant,Recombinant Chimeric Proteins,Recombinant Hybrid Proteins,Chimeric Protein, Recombinant,Fusion Protein, Recombinant,Hybrid Protein, Recombinant,Protein, Recombinant Chimeric,Protein, Recombinant Fusion,Protein, Recombinant Hybrid,Proteins, Recombinant Chimeric,Proteins, Recombinant Fusion,Proteins, Recombinant Hybrid
D000455 Medicago sativa A plant species of the family FABACEAE widely cultivated for ANIMAL FEED. Alfalfa,Lucerne
D000595 Amino Acid Sequence The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION. Protein Structure, Primary,Amino Acid Sequences,Sequence, Amino Acid,Sequences, Amino Acid,Primary Protein Structure,Primary Protein Structures,Protein Structures, Primary,Structure, Primary Protein,Structures, Primary Protein
D014157 Transcription Factors Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process. Transcription Factor,Factor, Transcription,Factors, Transcription
D016335 Zinc Fingers Motifs in DNA- and RNA-binding proteins whose amino acids are folded into a single structural unit around a zinc atom. In the classic zinc finger, one zinc atom is bound to two cysteines and two histidines. In between the cysteines and histidines are 12 residues which form a DNA binding fingertip. By variations in the composition of the sequences in the fingertip and the number and spacing of tandem repeats of the motif, zinc fingers can form a large number of different sequence specific binding sites. Zinc Finger DNA-Binding Domains,Zinc Finger Motifs,Finger, Zinc,Fingers, Zinc,Motif, Zinc Finger,Motifs, Zinc Finger,Zinc Finger,Zinc Finger DNA Binding Domains,Zinc Finger Motif
D016373 DNA, Antisense DNA that is complementary to the sense strand. (The sense strand has the same sequence as the mRNA transcript. The antisense strand is the template for mRNA synthesis.) Synthetic antisense DNAs are used to hybridize to complementary sequences in target RNAs or DNAs to effect the functioning of specific genes for investigative or therapeutic purposes. Antisense DNA,Anti-Sense DNA,Anti Sense DNA,DNA, Anti-Sense
D016962 Sinorhizobium meliloti A species of gram-negative, aerobic bacteria that causes formation of root nodules on some, but not all, types of sweet clover, MEDICAGO SATIVA, and fenugreek. Ensifer meliloti,Rhizobium meliloti

Related Publications

F Frugier, and S Poirier, and B Satiat-Jeunemaître, and A Kondorosi, and M Crespi
August 2012, Molecules and cells,
F Frugier, and S Poirier, and B Satiat-Jeunemaître, and A Kondorosi, and M Crespi
January 2012, Breeding science,
F Frugier, and S Poirier, and B Satiat-Jeunemaître, and A Kondorosi, and M Crespi
January 2014, PloS one,
F Frugier, and S Poirier, and B Satiat-Jeunemaître, and A Kondorosi, and M Crespi
January 1994, Blood,
F Frugier, and S Poirier, and B Satiat-Jeunemaître, and A Kondorosi, and M Crespi
March 2023, Breeding science,
F Frugier, and S Poirier, and B Satiat-Jeunemaître, and A Kondorosi, and M Crespi
January 2013, PloS one,
F Frugier, and S Poirier, and B Satiat-Jeunemaître, and A Kondorosi, and M Crespi
August 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research,
F Frugier, and S Poirier, and B Satiat-Jeunemaître, and A Kondorosi, and M Crespi
July 2018, Science (New York, N.Y.),
F Frugier, and S Poirier, and B Satiat-Jeunemaître, and A Kondorosi, and M Crespi
May 2009, Nucleic acids research,
F Frugier, and S Poirier, and B Satiat-Jeunemaître, and A Kondorosi, and M Crespi
October 2017, Archivum immunologiae et therapiae experimentalis,
Copied contents to your clipboard!