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Hyperbranched polyesteramides (DA2), prepared from hexahydrophthalic anhydride (D) and diisopropanolamine (A) have been characterized, by use of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS), field desorption (FD)-MS, and electrospray ionization (ESI)-MS. MALDI of polyesteramides produces protonated molecules. The spectra show a complex chemical composition distribution and end-group distribution which are mainly composed of two series of homologous oligomers DnA(n)+1 - mH2O and DnA(n) - mH2O, where m = 1-2. Signals from protonated molecules DnAn+1 and DnAn are almost absent in the MALDI spectrum, whereas these ions are responsible for the base peak of DnA(n)+1 - mH2O and DnA(n) - mH2O (m = 1-2) clusters in the ESI spectrum. The absence of -OH end-groups signals in the MALDI spectrum is due to a metastable decay of protonated DnA(n)+1 and DnAn ions in the ion source of the MALDI mass spectrometer prior to ion extraction. In-source decay results in the formation of protonated lower DnA(n)+1 - mH2O and DnA(n) - mH2O oligomers and their corresponding neutrals, leading to wrong conclusions concerning the relative end-group distribution as a function of the degree of polymerization and the chemical composition.
D Muscat, and
H Henderickx, and
G Kwakkenbos, and
R van Benthem, and
C G de Koster, and
R Fokkens, and
N M Nibbering
April 2001,
Journal of the American Society for Mass Spectrometry,
D Muscat, and
H Henderickx, and
G Kwakkenbos, and
R van Benthem, and
C G de Koster, and
R Fokkens, and
N M Nibbering
January 1997,
Rapid communications in mass spectrometry : RCM,
D Muscat, and
H Henderickx, and
G Kwakkenbos, and
R van Benthem, and
C G de Koster, and
R Fokkens, and
N M Nibbering
January 2005,
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D Muscat, and
H Henderickx, and
G Kwakkenbos, and
R van Benthem, and
C G de Koster, and
R Fokkens, and
N M Nibbering
January 2019,
Advances in experimental medicine and biology,
D Muscat, and
H Henderickx, and
G Kwakkenbos, and
R van Benthem, and
C G de Koster, and
R Fokkens, and
N M Nibbering
April 2003,
Journal of the American Society for Mass Spectrometry,
D Muscat, and
H Henderickx, and
G Kwakkenbos, and
R van Benthem, and
C G de Koster, and
R Fokkens, and
N M Nibbering
September 2011,
Rapid communications in mass spectrometry : RCM,
D Muscat, and
H Henderickx, and
G Kwakkenbos, and
R van Benthem, and
C G de Koster, and
R Fokkens, and
N M Nibbering
January 2005,
Rapid communications in mass spectrometry : RCM,
D Muscat, and
H Henderickx, and
G Kwakkenbos, and
R van Benthem, and
C G de Koster, and
R Fokkens, and
N M Nibbering
December 2000,
Journal of the American Society for Mass Spectrometry,
D Muscat, and
H Henderickx, and
G Kwakkenbos, and
R van Benthem, and
C G de Koster, and
R Fokkens, and
N M Nibbering
January 2000,
Analytical biochemistry,
D Muscat, and
H Henderickx, and
G Kwakkenbos, and
R van Benthem, and
C G de Koster, and
R Fokkens, and
N M Nibbering
July 2011,
Rapid communications in mass spectrometry : RCM,
