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Male Wistar rats were subjected to streptozotocin administration (85 mg/kg i.p.) and to cerebral air embolia with common carotids ligation. Electron microscope studies showed dark neurons, degeneration of endothelial cells and changes in basement membrane of brain capillaries, and changed astroglia in diabetic rats. Our results seem to support our previous findings in light microscopy and correspond with some others authors' suggestions that diabetes leads to chronic, generalized pathologic process in diabetic-rat brain, not-only dependent on vascular pathology, but which may be related to an oxidative/metabolic stress leading to a death of neurons in necrotic or apoptotic way.
P Piotrowski, and
B Gajkowska, and
H Olszewska, and
M Smiałek
January 1999,
Folia neuropathologica,
P Piotrowski, and
B Gajkowska, and
H Olszewska, and
M Smiałek
January 1986,
Nihon geka hokan. Archiv fur japanische Chirurgie,
P Piotrowski, and
B Gajkowska, and
H Olszewska, and
M Smiałek
January 1977,
Verhandlungen der Anatomischen Gesellschaft,
P Piotrowski, and
B Gajkowska, and
H Olszewska, and
M Smiałek
January 1983,
Patologia polska,
P Piotrowski, and
B Gajkowska, and
H Olszewska, and
M Smiałek
January 1975,
Stroke,
P Piotrowski, and
B Gajkowska, and
H Olszewska, and
M Smiałek
February 1971,
The British journal of ophthalmology,
P Piotrowski, and
B Gajkowska, and
H Olszewska, and
M Smiałek
January 1971,
Virchows Archiv. B, Cell pathology,
P Piotrowski, and
B Gajkowska, and
H Olszewska, and
M Smiałek
January 1992,
[Hokkaido igaku zasshi] The Hokkaido journal of medical science,
P Piotrowski, and
B Gajkowska, and
H Olszewska, and
M Smiałek
January 1986,
Neurobiology of aging,
P Piotrowski, and
B Gajkowska, and
H Olszewska, and
M Smiałek
May 1969,
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica,
