BIOMAT Database Logo BIOMAT Database Logo

Absolute configuration of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol formed metabolically from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. 2000

Hecht, and Spratt, and Trushin

UI MeSH Term Description Entries

Related Publications

Hecht, and Spratt, and Trushin
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
September 1985, IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans,
Hecht, and Spratt, and Trushin
Glucuronidation of 4-((hydroxymethyl)nitrosamino)-1-(3-pyridyl)-1-butanone, a metabolically activated form of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, by phenobarbital-treated rats.
January 1995, Chemical research in toxicology,
Hecht, and Spratt, and Trushin
DNA and hemoglobin alkylation by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its major metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F344 rats.
September 1988, Carcinogenesis,
Hecht, and Spratt, and Trushin
Effects of deuterium substitution on the tumorigenicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in A/J mice.
June 1990, Carcinogenesis,
Hecht, and Spratt, and Trushin
Genetic variability in the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL).
March 2012, International journal of cancer,
Hecht, and Spratt, and Trushin
Carcinogenicity and DNA adduct formation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F-344 rats.
December 2014, Carcinogenesis,
Hecht, and Spratt, and Trushin
Disposition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in bile duct-cannulated rats: stereoselective metabolism and tissue distribution.
January 2002, Carcinogenesis,
Hecht, and Spratt, and Trushin
Methyl DNA Phosphate Adduct Formation in Rats Treated Chronically with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of Its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol.
January 2018, Chemical research in toxicology,
Hecht, and Spratt, and Trushin
Effects of long term dietary phenethyl isothiocyanate on the microsomal metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F344 rats.
September 1997, Carcinogenesis,
Hecht, and Spratt, and Trushin
Mitochondrial DNA adducts in the lung and liver of F344 rats chronically treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and (S)-4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
February 2009, Chemical research in toxicology,
Copied contents to your clipboard!