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Bone metastasis infrequently appears as the first manifestation of hepatocellular calcinoma (HCC), and in any case in most patients the primary tumour is detected a few months after its development. We report the case of a patient with alcoholic liver disease, increased levels of alpha-fetoprotein, and no evidence of hepatic lesion in the different imaging modalities, in whom metastasis of HCC was detected in the ribs, whereas the primary tumour was not diagnosed until 15 months later. We believe that all patients with increased levels of alpha-fetoprotein should be tested in an intensified search for HCC and possible metastases, given that hepatic lesions may not be detected until many months alter the diagnosis of metastatic disease.
S Soto, and
T Artaza, and
R Gomez, and
F I Camacho, and
I Rodriguez, and
C Gonzalez, and
J L Potenciano, and
R Rodriguez
October 2000,
Gastroenterologie clinique et biologique,
S Soto, and
T Artaza, and
R Gomez, and
F I Camacho, and
I Rodriguez, and
C Gonzalez, and
J L Potenciano, and
R Rodriguez
January 2009,
General thoracic and cardiovascular surgery,
S Soto, and
T Artaza, and
R Gomez, and
F I Camacho, and
I Rodriguez, and
C Gonzalez, and
J L Potenciano, and
R Rodriguez
August 1999,
Fukuoka igaku zasshi = Hukuoka acta medica,
S Soto, and
T Artaza, and
R Gomez, and
F I Camacho, and
I Rodriguez, and
C Gonzalez, and
J L Potenciano, and
R Rodriguez
January 2024,
Radiology case reports,
S Soto, and
T Artaza, and
R Gomez, and
F I Camacho, and
I Rodriguez, and
C Gonzalez, and
J L Potenciano, and
R Rodriguez
October 1991,
Revue du rhumatisme et des maladies osteo-articulaires,
S Soto, and
T Artaza, and
R Gomez, and
F I Camacho, and
I Rodriguez, and
C Gonzalez, and
J L Potenciano, and
R Rodriguez
April 2014,
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu,
S Soto, and
T Artaza, and
R Gomez, and
F I Camacho, and
I Rodriguez, and
C Gonzalez, and
J L Potenciano, and
R Rodriguez
January 2010,
Gastroenterologie clinique et biologique,
S Soto, and
T Artaza, and
R Gomez, and
F I Camacho, and
I Rodriguez, and
C Gonzalez, and
J L Potenciano, and
R Rodriguez
December 1999,
Gastroenterologie clinique et biologique,
S Soto, and
T Artaza, and
R Gomez, and
F I Camacho, and
I Rodriguez, and
C Gonzalez, and
J L Potenciano, and
R Rodriguez
November 2012,
Gan to kagaku ryoho. Cancer & chemotherapy,
S Soto, and
T Artaza, and
R Gomez, and
F I Camacho, and
I Rodriguez, and
C Gonzalez, and
J L Potenciano, and
R Rodriguez
July 2003,
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology,
