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Our objective was to characterize retroviral sequences by RT-PCR with gag and env primers on RNA from RT-positive retroviral particles produced by multiple sclerosis (MS) derived B-lymphoblastoid cell lines. Sequence variants with high homology to the potentially functional subgroup RGH of the human endogenous retrovirus RTVL-H/HERV-H family were found. The same sequences were also specifically found in the particulate fraction of a series of MS patient plasma samples and were absent in controls. South-Western blots demonstrate the presence of a nucleic acid binding protein, corresponding in size and function to the nucleocapsid protein, Gag NC, of other retroviruses. We also present indications for transmission of the retrovirus to PHA-stimulated lymphocytes from healthy individuals.
T Christensen, and
P Dissing Sørensen, and
H Riemann, and
H J Hansen, and
M Munch, and
S Haahr, and
A Møller-Larsen
June 2011,
Acta neurologica Scandinavica,
T Christensen, and
P Dissing Sørensen, and
H Riemann, and
H J Hansen, and
M Munch, and
S Haahr, and
A Møller-Larsen
March 2008,
AIDS research and human retroviruses,
T Christensen, and
P Dissing Sørensen, and
H Riemann, and
H J Hansen, and
M Munch, and
S Haahr, and
A Møller-Larsen
April 2020,
Scientific reports,
T Christensen, and
P Dissing Sørensen, and
H Riemann, and
H J Hansen, and
M Munch, and
S Haahr, and
A Møller-Larsen
October 1998,
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie,
T Christensen, and
P Dissing Sørensen, and
H Riemann, and
H J Hansen, and
M Munch, and
S Haahr, and
A Møller-Larsen
March 2015,
Neurology,
T Christensen, and
P Dissing Sørensen, and
H Riemann, and
H J Hansen, and
M Munch, and
S Haahr, and
A Møller-Larsen
January 2020,
Journal of neuroimmunology,
T Christensen, and
P Dissing Sørensen, and
H Riemann, and
H J Hansen, and
M Munch, and
S Haahr, and
A Møller-Larsen
July 2008,
PloS one,
T Christensen, and
P Dissing Sørensen, and
H Riemann, and
H J Hansen, and
M Munch, and
S Haahr, and
A Møller-Larsen
January 2014,
Retrovirology,
T Christensen, and
P Dissing Sørensen, and
H Riemann, and
H J Hansen, and
M Munch, and
S Haahr, and
A Møller-Larsen
November 2009,
Retrovirology,
T Christensen, and
P Dissing Sørensen, and
H Riemann, and
H J Hansen, and
M Munch, and
S Haahr, and
A Møller-Larsen
December 2007,
International journal of biomedical science : IJBS,
