Postnatal growth in southern Chinese children with symptomatic congenital heart disease. 2000

E G Jacobs, and M P Leung, and J P Karlberg
Department of Paediatrics, The University of Hong Kong, Grantham Hospital, SAR, China.

Many Western children with congenital heart disease (CHD) show significant growth retardation. In this study postnatal growth was examined in Chinese children with symptomatic CHD in Hong Kong, in relation to their diagnosis and the time of surgery. 363 children of four years old or younger, who were admitted at Grantham Hospital, Hong Kong, in 1994 and 1995, were subdivided into six diagnostic categories and categorised into cyanotic and acyanotic groups. While a reduced birth weight SDS was present in 18% of patients, at the time of operation approximately 40% of them had subnormal weight and height values. Girls were more impaired in weight and weight-for-height than boys (-1.90 SDS vs -1.52 SDS, and -0.90 SDS vs -0.46 SDS, respectively). Children with acyanotic lesions were more affected in growth than those with cyanotic lesions, but they were also operated on at an older age than children in the latter group. Left to right shunt and common intracardiac mixing were particularly associated with wasting; transposition of the great arteries and pulmonary outflow tract obstruction with stunting; while children with left ventricular outflow obstruction revealed a proportional growth retardation in weight and height. Age at operation did not seem to have an independent effect on postnatal growth in children with CHD. As with Western children, growth retardation is a common feature in Chinese children with symptomatic cardiac defects. Haemodynamics, age at operation and nutritional influences are discussed as potential aetiologic factors.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D008297 Male Males
D001724 Birth Weight The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms. Birthweight,Birth Weights,Birthweights,Weight, Birth,Weights, Birth
D001827 Body Height The distance from the sole to the crown of the head with body standing on a flat surface and fully extended. Body Heights,Height, Body,Heights, Body
D001835 Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. Body Weights,Weight, Body,Weights, Body
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D002681 China A country spanning from central Asia to the Pacific Ocean. Inner Mongolia,Manchuria,People's Republic of China,Sinkiang,Mainland China
D003490 Cyanosis A bluish or purplish discoloration of the skin and mucous membranes due to an increase in the amount of deoxygenated hemoglobin in the blood or a structural defect in the hemoglobin molecule. Cyanoses
D005260 Female Females

Related Publications

E G Jacobs, and M P Leung, and J P Karlberg
January 2013, Pediatrics,
E G Jacobs, and M P Leung, and J P Karlberg
March 1967, The Journal of pediatrics,
E G Jacobs, and M P Leung, and J P Karlberg
January 2011, International journal of cardiology,
E G Jacobs, and M P Leung, and J P Karlberg
May 1969, American journal of diseases of children (1960),
E G Jacobs, and M P Leung, and J P Karlberg
January 1987, The Journal of the Singapore Paediatric Society,
E G Jacobs, and M P Leung, and J P Karlberg
April 1969, Indian journal of pediatrics,
E G Jacobs, and M P Leung, and J P Karlberg
August 1969, American heart journal,
E G Jacobs, and M P Leung, and J P Karlberg
November 2013, The American journal of cardiology,
E G Jacobs, and M P Leung, and J P Karlberg
August 2004, Journal of advanced nursing,
E G Jacobs, and M P Leung, and J P Karlberg
May 2003, The Annals of thoracic surgery,
Copied contents to your clipboard!