Biomaterial Database

Comparison of iothalamate meglumine, metrizamide and iodophendylate in cerebral ventriculography. A clinical, radiological and histopathological study in the rat. 1975

J G Klee, and J Praestholm

Clinical, radiological and histopathological findings following cerebral ventriculography in the rat using the water-soluble contrast media iothalamate meglumine and metrizamide, and the oil-soluble iodophendylate are reported. Clinically, iothalamate meglumine caused convulsions, while there were no adverse reactions to the other media. Radiologically there was good visualizaiton of the ventricles with all media. Iodophendylate was retained in the ventricles for the duration of the experiment (up to 60 days), while the water-soluble media had disappeared within 20 minutes. Histologically there were no pathological changes attributable to the water-soluble media. Iodophendyalte led to enlargement of the ventricles, and macrophages containing oil were seen on the ependymal lining.

UI	MeSH Term	Description	Entries
D007462	Iodobenzenes	Any derivative of BENZENE that contains IODINE.
D007481	Iophendylate	An inert iodine-containing agent which is opaque to X-RAYS. It is used mainly for BRAIN and SPINAL CORD visualization.	Ethiodan,Iodophendylate,Iofendylate,Ioglunide,Isophendylate,Maiodil,Myodil,Panthopaque,Pantopaque
D007482	Iothalamate Meglumine	A radiopaque medium used for urography, angiography, venography, and myelography. It is highly viscous and binds to plasma proteins.	Iotalamate Meglumine,Iothalamic Acid Methylglucamine,Meglumine Iothalamate,Conray 60,Iothalamic Acid Meglumine,Meglumine Iotalamate,Methylglucamine Iotalamate,Methylglucamine Iothalamate,Iotalamate, Meglumine,Iotalamate, Methylglucamine,Iothalamate, Meglumine,Iothalamate, Methylglucamine,Meglumine, Iotalamate,Meglumine, Iothalamate,Meglumine, Iothalamic Acid,Methylglucamine, Iothalamic Acid
D007483	Iothalamic Acid	A contrast medium in diagnostic radiology with properties similar to those of diatrizoic acid. It is used primarily as its sodium and meglumine (IOTHALAMATE MEGLUMINE) salts.	Iotalamic Acid,Methalamic Acid,Angio-Conray,Conray 420,Iodothalamate,Iothalamate,Iothalamic Acid, Calcium (2:1) Salt,Iothalamic Acid, Monosilver (1+) Salt,Iothalamic Acid, Monosodium Salt,Iothalamic Acid, Monosodium Salt, Dimer,Lopamidol,Sodium Iothalamate,Acid, Iotalamic,Acid, Iothalamic,Acid, Methalamic,Angio Conray,AngioConray,Iothalamate, Sodium
D008297	Male		Males
D008793	Metrizamide	A solute for density gradient centrifugation offering higher maximum solution density without the problems of increased viscosity. It is also used as a resorbable, non-ionic contrast medium.	Amipak,Amipaque
D003287	Contrast Media	Substances used to allow enhanced visualization of tissues.	Radiopaque Media,Contrast Agent,Contrast Agents,Contrast Material,Contrast Materials,Radiocontrast Agent,Radiocontrast Agents,Radiocontrast Media,Agent, Contrast,Agent, Radiocontrast,Agents, Contrast,Agents, Radiocontrast,Material, Contrast,Materials, Contrast,Media, Contrast,Media, Radiocontrast,Media, Radiopaque
D005069	Evaluation Studies as Topic	Works about studies that determine the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies.	Critique,Evaluation Indexes,Evaluation Methodology,Evaluation Report,Evaluation Research,Methodology, Evaluation,Pre-Post Tests,Qualitative Evaluation,Quantitative Evaluation,Theoretical Effectiveness,Use-Effectiveness,Critiques,Effectiveness, Theoretical,Evaluation Methodologies,Evaluation Reports,Evaluation, Qualitative,Evaluation, Quantitative,Evaluations, Qualitative,Evaluations, Quantitative,Indexes, Evaluation,Methodologies, Evaluation,Pre Post Tests,Pre-Post Test,Qualitative Evaluations,Quantitative Evaluations,Report, Evaluation,Reports, Evaluation,Research, Evaluation,Test, Pre-Post,Tests, Pre-Post,Use Effectiveness
D005260	Female		Females
D000617	Aminoglycosides	Glycosylated compounds in which there is an amino substituent on the glycoside. Some of them are clinically important ANTIBIOTICS.	Aminoglycoside