Biomaterial Database

Plasma volume expansion for suspected impaired fetal growth. 2000

A M Gülmezoglu, and G J Hofmeyr

Special Department of Research, Development and Research Training in Human Reproduction, UNDP/UNFPA/WHO/World Bank, World Health Organisation, Geneva 27, Switzerland, CH-1211. gulmezoglum@who.ch

BACKGROUND Failure of the normal expansion of plasma volume in the mother is associated with impaired fetal growth and pre-eclampsia. OBJECTIVE The objective of this review was to assess the effects of plasma volume expansion for suspected impaired fetal growth. METHODS We searched the Cochrane Pregnancy and Childbirth Group trials register and the Cochrane Controlled Trials Register. Date of last search: December 1999. METHODS Randomized or quasi-randomized trials of plasma volume expansion compared to no plasma volume expansion in women with suspected impaired fetal growth. METHODS Trial quality was assessed. RESULTS No studies were included. CONCLUSIONS There is not enough evidence to evaluate the use of plasma volume expansion for suspected impaired fetal growth.

UI	MeSH Term	Description	Entries
D010952	Plasma Substitutes	Any liquid used to replace blood plasma, usually a saline solution, often with serum albumins, dextrans or other preparations. These substances do not enhance the oxygen- carrying capacity of blood, but merely replace the volume. They are also used to treat dehydration.	Blood Expanders,Plasma Volume Expanders,Expanders, Blood,Expanders, Plasma Volume,Substitutes, Plasma,Volume Expanders, Plasma
D010953	Plasma Volume	Volume of PLASMA in the circulation. It is usually measured by INDICATOR DILUTION TECHNIQUES.	Blood Plasma Volume,Blood Plasma Volumes,Plasma Volumes,Volume, Blood Plasma,Volume, Plasma,Volumes, Blood Plasma,Volumes, Plasma
D011247	Pregnancy	The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	Gestation,Pregnancies
D005260	Female		Females
D005317	Fetal Growth Retardation	Failure of a FETUS to attain expected GROWTH.	Growth Retardation, Intrauterine,Intrauterine Growth Retardation,Fetal Growth Restriction,Intrauterine Growth Restriction
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man