-transparent.png){kind=logo}
Rabbit kappa light (L) chain allotypes are controlled by the allelic genes b4, b5, b6, b9 and a recently described allele b4v. The product of the b4v gene differs from that of b4 by at least two amino acid substitutions in the constant region. A serologic distinction between the b4 and b4v allotyes has now been detected by a radioimmune assay using one of six anti-b4 sera tested. The distinction was enhanced by fractionation of this antiserum on an immunoadsorbent containing cottontail rabbit IgG. IgG with L chains of the b4v type are deficient in their ability to inhibit binding of b4 IgG to the antibody preparation. L chains isolated from b4 and b4v IgG samples could not be distinguished by this assay indicating that interaction with an H chain is required for expression of the L chain determinants that differentiate b4 from b4v.
L J Smith, and
J A Sogh, and
T J Kindt, and
W J Mandy
July 1983,
Proceedings of the National Academy of Sciences of the United States of America,
L J Smith, and
J A Sogh, and
T J Kindt, and
W J Mandy
January 1984,
Annales d'immunologie,
L J Smith, and
J A Sogh, and
T J Kindt, and
W J Mandy
September 1983,
Proceedings of the National Academy of Sciences of the United States of America,
L J Smith, and
J A Sogh, and
T J Kindt, and
W J Mandy
August 1976,
Journal of immunology (Baltimore, Md. : 1950),
L J Smith, and
J A Sogh, and
T J Kindt, and
W J Mandy
May 1974,
Proceedings of the National Academy of Sciences of the United States of America,
L J Smith, and
J A Sogh, and
T J Kindt, and
W J Mandy
October 1989,
Research in immunology,
L J Smith, and
J A Sogh, and
T J Kindt, and
W J Mandy
April 1981,
European journal of immunology,
L J Smith, and
J A Sogh, and
T J Kindt, and
W J Mandy
January 1995,
Immunogenetics,
L J Smith, and
J A Sogh, and
T J Kindt, and
W J Mandy
February 1976,
Archives internationales de physiologie et de biochimie,
L J Smith, and
J A Sogh, and
T J Kindt, and
W J Mandy
January 1985,
Immunology letters,
